Editing Fibrosis (TRPM7)

{{tp|p=23934071|t=2013. Inhibition of TRPM7 channels prevents proliferation and differentiation of human lung fibroblasts.|pdf=|usr=}}{{23934071}}
{{tp|p=18268139|t=2008. Downregulation of renal TRPM7 and increased inflammation and fibrosis in aldosterone-infused mice: effects of magnesium.|pdf=|usr=}}{{18268139}}
{{tp|p=29500887|t=2018. TGFbeta-induced epithelial-to-mesenchymal transition in prostate cancer cells is mediated via TRPM7 expression.|pdf=|usr=}}{{29500887}}
{{tp|p=25204892|t=2015. Novel insights into TRPM7 function in fibrotic diseases: a potential therapeutic target.|pdf=|usr=}}{{25204892}}
{{tp|p=25150141|t=2014. TGF-beta1-elevated TRPM7 channel regulates collagen expression in hepatic stellate cells via TGF-beta1/Smad pathway.|pdf=|usr=}}{{25150141}}
{{tp|p=24680379|t=2014. TRPM7 is involved in angiotensin II induced cardiac fibrosis development by mediating calcium and magnesium influx.|pdf=|usr=}}{{24680379}}
{{tp|p=37072467|t=2023. CBGA ameliorates inflammation and fibrosis in nephropathy.|pdf=|usr=}}{{37072467}}
{{tp|p=36384264|t=2022. TRPM7 Elicits Proliferation and Differentiation of Human Lens Epithelial Cells through the TGF-beta/Smad Pathways.|pdf=|usr=}}{{36384264}}
{{tp|p=35883700|t=2022. TRPM7 Modulates Human Pancreatic Stellate Cell Activation.|pdf=|usr=}}{{35883700}}
{{tp|p=35864199|t=2022. TRPM7 restrains plasmin activity and promotes transforming growth factor-beta1 signaling in primary human lung fibroblasts.|pdf=|usr=}}{{35864199}}
{{tp|p=33922466|t=2021. Channelling the Force to Reprogram the Matrix: Mechanosensitive Ion Channels in Cardiac Fibroblasts.|pdf=|usr=}}{{33922466}}
{{tp|p=33456540|t=2021. Role of TRPM7 in cardiac fibrosis: A potential therapeutic target (Review).|pdf=|usr=}}{{33456540}}
{{tp|p=33284571|t=2020. MiR-149 attenuates the proliferation and migration of TGF-beta1-induced airway smooth muscle cells by targeting TRPM7 and affecting downstream MAPK signal pathway.|pdf=|usr=}}{{33284571}}
{{tp|p=35850880|t=2023. Overexpression of TRPM7 promotes the therapeutic effect of curcumin in wound healing through the STAT3/SMAD3 signaling pathway in human fibroblasts.|pdf=|usr=}}{{35850880}}
{{tp|p=33647257|t=2021. Carvacrol alleviates liver fibrosis by inhibiting TRPM7 and modulating the MAPK signaling pathway.|pdf=|usr=}}{{33647257}}
{{tp|p=33494094|t=2021. Transient Receptor Potential Melastatin 7 Promotes Vascular Adventitial Fibroblasts Phenotypic Transformation and Inflammatory Reaction Induced by Mechanical Stretching Stress via p38 MAPK/JNK Pathway.|pdf=|usr=}}{{33494094}}
{{tp|p=33143990|t=2021. Panax Notoginseng Saponins suppresses TRPM7 via the PI3K/AKT pathway to inhibit hypertrophic scar formation in vitro.|pdf=|usr=}}{{33143990}}
{{tp|p=31739105|t=2020. Astragaloside IV inhibits cardiac fibrosis via miR-135a-TRPM7-TGF-beta/Smads pathway.|pdf=|usr=}}{{31739105}}
{{tp|p=31640089|t=2019. TRPM7 deficiency suppresses cell proliferation, migration, and invasion in human colorectal cancer via regulation of epithelial-mesenchymal transition.|pdf=|usr=}}{{31640089}}
{{tp|p=30445149|t=2019. TRP channels in cardiac and intestinal fibrosis.|pdf=|usr=}}{{30445149}}
{{tp|p=30290314|t=2018. TGF-beta1-Induced Airway Smooth Muscle Cell Proliferation Involves TRPM7-Dependent Calcium Influx via TGFbetaR/SMAD3.|pdf=|usr=}}{{30290314}}
{{tp|p=29775892|t=2018. MicroRNA-135a inhibits cardiac fibrosis induced by isoproterenol via TRPM7 channel.|pdf=|usr=}}{{29775892}}
{{tp|p=29079194|t=2017. Role of ROS-TRPM7-ERK1/2 axis in high concentration glucose-mediated proliferation and phenotype switching of rat aortic vascular smooth muscle cells.|pdf=|usr=}}{{29079194}}
{{tp|p=28573641|t=2017. Downregulation of TRPM7 suppressed migration and invasion by regulating epithelial-mesenchymal transition in prostate cancer cells.|pdf=|usr=}}{{28573641}}
{{tp|p=28393175|t=2017. TRPM7 channels mediate the functional changes in cardiac fibroblasts induced by angiotensin II.|pdf=|usr=}}{{28393175}}
{{tp|p=32706027|t=2020. Epidermal growth factor signaling through transient receptor potential melastatin 7 cation channel regulates vascular smooth muscle cell function.|pdf=|usr=}}{{32706027}}
{{tp|p=32047249|t=2020. TRPM7 contributes to progressive nephropathy.|pdf=|usr=}}{{32047249}}
{{tp|p=30819230|t=2019. TRPM7 promotes the epithelial-mesenchymal transition in ovarian cancer through the calcium-related PI3K / AKT oncogenic signaling.|pdf=|usr=}}{{30819230}}
{{tp|p=29684587|t=2018. TRPM7 controls mesenchymal features of breast cancer cells by tensional regulation of SOX4.|pdf=|usr=}}{{29684587}}
{{tp|p=29511803|t=2018. TRPM7 regulates angiotensin II-induced sinoatrial node fibrosis in sick sinus syndrome rats by mediating Smad signaling.|pdf=|usr=}}{{29511803}}
{{tp|p=26164719|t=2015. Inhibition of TRPM7 Attenuates Rat Aortic Smooth Muscle Cell Proliferation Induced by Angiotensin II: Role of Genistein.|pdf=|usr=}}{{26164719}}
{{tp|p=25863514|t=2015. Effects of laser irradiation at different wavelengths (660, 810, 980, and 1064 nm) on transient receptor potential melastatin channels in an animal model of wound healing.|pdf=|usr=}}{{25863514}}
{{tp|p=27108806|t=2016. Upregulation of TRPM7 augments cell proliferation and interleukin-8 release in airway smooth muscle cells of rats exposed to cigarette smoke.|pdf=|usr=}}{{27108806}}
{{tp|p=26900082|t=2016. TRPM7 channel regulates ox-LDL-induced proliferation and migration of vascular smooth muscle cells via MEK-ERK pathways.|pdf=|usr=}}{{26900082}}
{{tp|p=24220678|t=2014. Blockage of TRPM7 channel induces hepatic stellate cell death through endoplasmic reticulum stress-mediated apoptosis.|pdf=|usr=}}{{24220678}}
{{tp|p=23958495|t=2013. TRPM7 channel regulates PDGF-BB-induced proliferation of hepatic stellate cells via PI3K and ERK pathways.|pdf=|usr=}}{{23958495}}
{{tp|p=24871786|t=2014. Transient receptor potential melastatin 7 (TRPM7) contributes to H2O2-induced cardiac fibrosis via mediating Ca(2+) influx and extracellular signal-regulated kinase 1/2 (ERK1/2) activation in cardiac fibroblasts.|pdf=|usr=}}{{24871786}}
{{tp|p=24710004|t=2014. Endotoxin induces fibrosis in vascular endothelial cells through a mechanism dependent on transient receptor protein melastatin 7 activity.|pdf=|usr=}}{{24710004}}
{{tp|p=24586847|t=2014. Magnesium inhibits Wnt/beta-catenin activity and reverses the osteogenic transformation of vascular smooth muscle cells.|pdf=|usr=}}{{24586847}}
{{tp|p=23686305|t=2014. Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent.|pdf=|usr=}}{{23686305}}
{{tp|p=23511028|t=2013. A TRP to cardiac fibroblast differentiation.|pdf=|usr=}}{{23511028}}
{{tp|p=23432060|t=2013. Transient receptor potential (TRP) channels and cardiac fibrosis.|pdf=|usr=}}{{23432060}}
{{tp|p=20075334|t=2010. TRPM7-mediated Ca2+ signals confer fibrogenesis in human atrial fibrillation.|pdf=|usr=}}{{20075334}}
{{tp|p=36747205|t=2023. Empagliflozin suppressed cardiac fibrogenesis through sodium-hydrogen exchanger inhibition and modulation of the calcium homeostasis.|pdf=|usr=}}{{36747205}}
{{tp|p=34331987|t=2021. Fibrosis of the diabetic heart: Clinical significance, molecular mechanisms, and therapeutic opportunities.|pdf=|usr=}}{{34331987}}
{{tp|p=28506744|t=2017. Hepatic stellate cells as key target in liver fibrosis.|pdf=|usr=}}{{28506744}}
{{tp|p=37138582|t=2023. Integrating Network Pharmacology and Experimental Validation to Explore the Pharmacological Mechanism of Astragaloside IV in Treating Bleomycin-Induced Pulmonary Fibrosis.|pdf=|usr=}}{{37138582}}
{{tp|p=36408254|t=2022. Astragalus and its formulas as a therapeutic option for fibrotic diseases: Pharmacology and mechanisms.|pdf=|usr=}}{{36408254}}
{{tp|p=36160396|t=2022. Astragalus Mongholicus: A review of its anti-fibrosis properties.|pdf=|usr=}}{{36160396}}
{{tp|p=35656031|t=2022. Astragaloside IV Ameliorates Isoprenaline-Induced Cardiac Fibrosis in Mice via Modulating Gut Microbiota and Fecal Metabolites.|pdf=|usr=}}{{35656031}}
{{tp|p=34811833|t=2022. Sorafenib attenuates liver fibrosis by triggering hepatic stellate cell ferroptosis via HIF-1alpha/SLC7A11 pathway.|pdf=|usr=}}{{34811833}}
{{tp|p=34594406|t=2021. Se alleviates homocysteine-induced fibrosis in cardiac fibroblasts via downregulation of lncRNA MEG3.|pdf=|usr=}}{{34594406}}
{{tp|p=36277193|t=2022. Ion channels as a therapeutic target for renal fibrosis.|pdf=|usr=}}{{36277193}}
{{tp|p=33082445|t=2020. Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models.|pdf=|usr=}}{{33082445}}