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*''Monoclonal immunoglobulin diseases include light-chain deposition disease, light- and heavy-chain deposition disease,heavy-chain deposition disease, type I cryoglobulinemia, immune tubular glomerulopathy and fibrillar glomerulopathy. In recent years, the spectrum of monoclonal gammopathy has gradually expanded to include tissue deposits of monoisotype Ig but lacks evidence for a circulating monoclonal Ig component.'' *''fibrillary glomerulopathy, cryoglobulinemia type 1, membranous glomerulonephritis with IgGฮบ deposition, light-chain amyloidosis, light- and heavy-chain deposition disease, lupus nephritis, atypical anti-GBM nephritis with IgG deposition and idiopathic MPGN.'' *daratumumab ==anti cd38 *0.8% of kidney biopsies *20% terminal ki; 90% graft recurrence w early graft loss. *nephritic/nphrotic init. *no cryoglobulins (dd: cryo-crystalglobulinemic disease)
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