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Toxic cations (TRPM7)
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{{tp|p=30523498|t=2019. Cobalt Administration Causes Reduced Contractility with Parallel Increases in TRPC6 and TRPM7 Transporter Protein Expression in Adult Rat Hearts.|pdf=|usr=}}{{30523498}} {{tp|p=28696294|t=2017. TRPM7 senses oxidative stress to release Zn(2+) from unique intracellular vesicles.|pdf=|usr=}}{{28696294}} {{tp|p=12508053|t=2003. TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions.|pdf=|usr=}}{{12508053}} {{tp|p=30508321|t=2019. Periprosthetic hypoxia as consequence of TRPM7 mediated cobalt influx in osteoblasts.|pdf=|usr=}}{{30508321}} {{tp|p=26780729|t=2016. Stress hormone potentiates Zn(2+)-induced neurotoxicity via TRPM7 channel in dopaminergic neuron.|pdf=|usr=}}{{26780729}} {{tp|p=23602937|t=2013. Oxidative stress-modulated TRPM ion channels in cell dysfunction and pathological conditions in humans.|pdf=|usr=}}{{23602937}} {{tp|p=36430333|t=2022. Carvacrol Inhibits Expression of Transient Receptor Potential Melastatin 7 Channels and Alleviates Zinc Neurotoxicity Induced by Traumatic Brain Injury.|pdf=|usr=}}{{36430333}} {{tp|p=36139480|t=2022. Transient Receptor Potential (TRP) Channels in Airway Toxicity and Disease: An Update.|pdf=|usr=}}{{36139480}} {{tp|p=34928937|t=2021. CNNM proteins selectively bind to the TRPM7 channel to stimulate divalent cation entry into cells.|pdf=|usr=}}{{34928937}} {{tp|p=33114331|t=2020. The Transient Receptor Potential Melastatin 7 (TRPM7) Inhibitors Suppress Seizure-Induced Neuron Death by Inhibiting Zinc Neurotoxicity.|pdf=|usr=}}{{33114331}} {{tp|p=32215176|t=2020. Suppression of TRPM7 Inhibited Hypoxia-Induced Migration and Invasion of Androgen-Independent Prostate Cancer Cells by Enhancing RACK1-Mediated Degradation of HIF-1alpha.|pdf=|usr=}}{{32215176}} {{tp|p=20932883|t=2010. Involvement of transient receptor potential melastatin-related 7 (TRPM7) channels in cadmium uptake and cytotoxicity in MC3T3-E1 osteoblasts.|pdf=|usr=}}{{20932883}} {{tp|p=18538363|t=2008. Characterization of cadmium uptake and cytotoxicity in human osteoblast-like MG-63 cells.|pdf=|usr=}}{{18538363}} {{tp|p=25169754|t=2015. Local anesthetic lidocaine inhibits TRPM7 current and TRPM7-mediated zinc toxicity.|pdf=|usr=}}{{25169754}} {{tp|p=21487014|t=2011. Hypoxia induces an increase in intracellular magnesium via transient receptor potential melastatin 7 (TRPM7) channels in rat hippocampal neurons in vitro.|pdf=|usr=}}{{21487014}} {{tp|p=20812867|t=2011. Pathophysiologically relevant levels of hydrogen peroxide induce glutamate-independent neurodegeneration that involves activation of transient receptor potential melastatin 7 channels.|pdf=|usr=}}{{20812867}} {{tp|p=20400517|t=2010. Neurotoxicity of zinc in vivo.|pdf=|usr=}}{{20400517}} {{tp|p=20048154|t=2010. Zinc-induced neurotoxicity mediated by transient receptor potential melastatin 7 channels.|pdf=|usr=}}{{20048154}} {{tp|p=16428268|t=2006. Manganese and iron transport across pulmonary epithelium.|pdf=|usr=}}{{16428268}} {{tp|p=37928257|t=2023. Potential Roles of Metals in the Pathogenesis of Pulmonary and Systemic Hypertension.|pdf=|usr=}}{{37928257}} {{tp|p=35897065|t=2022. Toxic metals in the regulation of epithelial-mesenchymal plasticity: demons or angels?|pdf=|usr=}}{{35897065}} {{tp|p=34053230|t=2021. Cobalt-induced cardiomyopathy - do circulating cobalt levels matter?|pdf=|usr=}}{{34053230}} {{tp|p=33875618|t=2021. Selenomethionine protects hematopoietic stem/progenitor cells against cobalt nanoparticles by stimulating antioxidant actions and DNA repair functions.|pdf=|usr=}}{{33875618}} {{tp|p=36105221|t=2022. Exposure of metal toxicity in Alzheimer's disease: An extensive review.|pdf=|usr=}}{{36105221}} {{tp|p=29114205|t=2017. Biometal Dyshomeostasis and Toxic Metal Accumulations in the Development of Alzheimer's Disease.|pdf=|usr=}}{{29114205}} {{tp|p=37511448|t=2023. Delineating Zinc Influx Mechanisms during Platelet Activation.|pdf=|usr=}}{{37511448}} {{tp|p=37047637|t=2023. Pathophysiological Roles of Transient Receptor Potential (Trp) Channels and Zinc Toxicity in Brain Disease.|pdf=|usr=}}{{37047637}} {{tp|p=23360507|t=2013. Manganese toxicity in the central nervous system: the glutamine/glutamate-gamma-aminobutyric acid cycle.|pdf=|usr=}}{{23360507}} {{tp|p=22457347|t=2012. Impact of manganese on and transfer across blood-brain and blood-cerebrospinal fluid barrier in vitro.|pdf=|usr=}}{{22457347}} {{tp|p=21197404|t=2010. The role of zinc in Alzheimer's disease.|pdf=|usr=}}{{21197404}} {{tp|p=12508053|t=2003. TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions.|pdf=|usr=}}{{12508053}} {{tp|p=35277059|t=2022. An Emerging Role of Defective Copper Metabolism in Heart Disease.|pdf=|usr=}}{{35277059}} {{tp|p=34422041|t=2021. Role of Autophagy in Cadmium-Induced Hepatotoxicity and Liver Diseases.|pdf=|usr=}}{{34422041}} {{tp|p=31571097|t=2019. Role of Astrocytes in Manganese Neurotoxicity Revisited.|pdf=|usr=}}{{31571097}} {{tp|p=31257486|t=2019. Geniposide attenuates cadmium‑induced oxidative stress injury via Nrf2 signaling in osteoblasts.|pdf=|usr=}}{{31257486}} {{tp|p=28620665|t=2017. Influence of iron metabolism on manganese transport and toxicity.|pdf=|usr=}}{{28620665}} {{tp|p=24470093|t=2013. Manganese in health and disease.|pdf=|usr=}}{{24470093}} {{tp|p=23595673|t=2013. Manganese homeostasis and transport.|pdf=|usr=}}{{23595673}} {{tp|p=21963226|t=2011. Role of manganese in neurodegenerative diseases.|pdf=|usr=}}{{21963226}} {{tp|p=19921534|t=2010. Manganese (Mn) and iron (Fe): interdependency of transport and regulation.|pdf=|usr=}}{{19921534}} {{tp|p=35202246|t=2022. Cobalt Neurotoxicity: Transcriptional Effect of Elevated Cobalt Blood Levels in the Rodent Brain.|pdf=|usr=}}{{35202246}} {{tp|p=34083604|t=2021. Evaluation of the immunomodulatory effects of cobalt, copper and magnesium ions in a pro inflammatory environment.|pdf=|usr=}}{{34083604}} {{tp|p=28751933|t=2017. The Central Role of Biometals Maintains Oxidative Balance in the Context of Metabolic and Neurodegenerative Disorders.|pdf=|usr=}}{{28751933}} {{tp|p=23776557|t=2013. Live-cell dynamic sensing of Cd(2+) with a FRET-based indicator.|pdf=|usr=}}{{23776557}} {{tp|p=22701362|t=2012. Effect of magnesium supplementation on the distribution patterns of zinc, copper, and magnesium in rabbits exposed to prolonged cadmium intoxication.|pdf=|usr=}}{{22701362}} {{tp|p=17084903|t=2007. Manganese neurotoxicity: a focus on the neonate.|pdf=|usr=}}{{17084903}} {{tp|p=36010579|t=2022. Main Cations and Cellular Biology of Traumatic Spinal Cord Injury.|pdf=|usr=}}{{36010579}} {{tp|p=32153368|t=2020. Mechanotransduction Activity Facilitates Hair Cell Toxicity Caused by the Heavy Metal Cadmium.|pdf=|usr=}}{{32153368}} {{tp|p=27558804|t=2016. Pleiotropic roles of Ca(+2)/calmodulin-dependent pathways in regulating cadmium-induced toxicity in human osteoblast-like cell lines.|pdf=|usr=}}{{27558804}} {{tp|p=20204475|t=2010. Catch me if you can! Novel aspects of cadmium transport in mammalian cells.|pdf=|usr=}}{{20204475}} {{tp|p=25169754|t=2015. Local anesthetic lidocaine inhibits TRPM7 current and TRPM7-mediated zinc toxicity.|pdf=|usr=}}{{25169754}} {{tp|p=20400517|t=2010. Neurotoxicity of zinc in vivo.|pdf=|usr=}}{{20400517}} {{tp|p=20037152|t=2010. Zn2+ activates large conductance Ca2+-activated K+ channel via an intracellular domain.|pdf=|usr=}}{{20037152}} {{tp|p=24758227|t=2014. Severe hypoxia exerts parallel and cell-specific regulation of gene expression and alternative splicing in human mesenchymal stem cells.|pdf=|usr=}}{{24758227}} {{tp|p=35252173|t=2022. Environmental Cadmium Exposure Promotes the Development, Progression and Chemoradioresistance of Esophageal Squamous Cell Carcinoma.|pdf=|usr=}}{{35252173}} {{tp|p=33946782|t=2021. The Multifaceted Roles of Zinc in Neuronal Mitochondrial Dysfunction.|pdf=|usr=}}{{33946782}} {{tp|p=29311807|t=2017. Alteration in Intracellular Zn(2+) Homeostasis as a Result of TRPM2 Channel Activation Contributes to ROS-Induced Hippocampal Neuronal Death.|pdf=|usr=}}{{29311807}} {{tp|p=35625809|t=2022. The Role of the Metabolism of Zinc and Manganese Ions in Human Cancerogenesis.|pdf=|usr=}}{{35625809}} {{tp|p=23594835|t=2013. Role of astrocytes in manganese mediated neurotoxicity.|pdf=|usr=}}{{23594835}} {{tp|p=37670938|t=2023. A novel defined risk signature of cuproptosis-related long non-coding RNA for predicting prognosis, immune infiltration, and immunotherapy response in lung adenocarcinoma.|pdf=|usr=}}{{37670938}} {{tp|p=31652790|t=2019. Zinc Homeostasis in Platelet-Related Diseases.|pdf=|usr=}}{{31652790}} {{tp|p=27384555|t=2016. Zinc as Allosteric Ion Channel Modulator: Ionotropic Receptors as Metalloproteins.|pdf=|usr=}}{{27384555}} {{tp|p=33460731|t=2021. The Function and Regulation of Zinc in the Brain.|pdf=|usr=}}{{33460731}} {{tp|p=31261654|t=2019. Manganese Uptake by A549 Cells is Mediated by Both ZIP8 and ZIP14.|pdf=|usr=}}{{31261654}} {{tp|p=33712543|t=2021. Zn(2+) influx activates ERK and Akt signaling pathways.|pdf=|usr=}}{{33712543}} {{tp|p=32080757|t=2020. Cadmium exposure enhances cell migration and invasion through modulated TRPM7 channel expression.|pdf=|usr=}}{{32080757}}
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