TRPM2

30467180 PDF 2018. Structures and gating mechanism of human TRPM2.Template:30467180
34788616 PDF 2021. Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel.Template:34788616
24174660 PDF 2013. Modulation of NMDAR subunit expression by TRPM2 channels regulates neuronal vulnerability to ischemic cell death.Template:24174660
20660597 PDF 2010. State-dependent inhibition of TRPM2 channel by acidic pH.Template:20660597
34845114 PDF 2021. Knockdown of transient receptor potential melastatin 2 reduces renal fibrosis and inflammation by blocking transforming growth factor-beta1-activated JNK1 activation in diabetic mice.Template:34845114
36238268 PDF 2022. Silencing TRPM2 enhanced erastin- and RSL3-induced ferroptosis in gastric cancer cells through destabilizing HIF-1alpha and Nrf2 proteins.Template:36238268
34299254 PDF 2021. The Role of TRPM2 in Endothelial Function and Dysfunction.Template:34299254
32899872 PDF 2020. Structure-Function Relationship of TRPM2: Recent Advances, Contradictions, and Open Questions.Template:32899872
25391657 PDF 2014. A splice variant of the human ion channel TRPM2 modulates neuroblastoma tumor growth through hypoxia-inducible factor (HIF)-1/2alpha.Template:25391657
21135052 PDF 2011. TRPM2: a multifunctional ion channel for calcium signalling.Template:21135052
19917732 PDF 2009. Modulation of TRPM2 by acidic pH and the underlying mechanisms for pH sensitivity.Template:19917732
31575956 PDF 2019. The Human Transient Receptor Potential Melastatin 2 Ion Channel Modulates ROS Through Nrf2.Template:31575956
36421426 PDF 2022. Citronellal Attenuates Oxidative Stress-Induced Mitochondrial Damage through TRPM2/NHE1 Pathway and Effectively Inhibits Endothelial Dysfunction in Type 2 Diabetes Mellitus.Template:36421426
34063677 PDF 2021. Reactive Oxygen Species-Induced TRPM2-Mediated Ca(2+) Signalling in Endothelial Cells.Template:34063677
22275755 PDF 2012. TRPM2 Ca2+ channel regulates energy balance and glucose metabolism.Template:22275755
29906250 PDF 2018. Oxidant sensor cation channel TRPM2 regulates neutrophil extracellular trap formation and protects against pneumoseptic bacterial infection.Template:29906250
29311807 PDF 2017. Alteration in Intracellular Zn(2+) Homeostasis as a Result of TRPM2 Channel Activation Contributes to ROS-Induced Hippocampal Neuronal Death.Template:29311807
29201240 PDF 2017. Glucagon-like peptide-1 potentiates glucose-stimulated insulin secretion via the transient receptor potential melastatin 2 channel.Template:29201240
28790198 PDF 2017. Neutrophil Activation of Endothelial Cell-Expressed TRPM2 Mediates Transendothelial Neutrophil Migration and Vascular Injury.Template:28790198
27317297 PDF 2016. Extended therapeutic window of a novel peptide inhibitor of TRPM2 channels following focal cerebral ischemia.Template:27317297
33924946 PDF 2021. Species-Specific Regulation of TRPM2 by PI(4,5)P(2) via the Membrane Interfacial Cavity.Template:33924946
31533549 PDF 2019. Transient receptor potential melastatin 2-mediated heme oxygenase-1 has a role for bacterial clearance by regulating autophagy in peritoneal macrophages during polymicrobial sepsis.Template:31533549
29495939 PDF 2018. Disruption of transient receptor potential melastatin 2 decreases elastase release and bacterial clearance in neutrophils.Template:29495939
25295536 PDF 2014. TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1.Template:25295536
31796045 PDF 2019. Transient receptor potential melastatin 2 channels are overexpressed in myalgic encephalomyelitis/chronic fatigue syndrome patients.Template:31796045
31431622 PDF 2019. Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel.Template:31431622
25059284 PDF 2014. Oxidative stress increases pulmonary vascular permeability in diabetic rats through activation of transient receptor potential melastatin 2 channels.Template:25059284
22101731 PDF 2011. The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation.Template:22101731
37649595 PDF 2023. TRPM2 protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction via modulating autophagy.Template:37649595
33927223 PDF 2021. TRPM2 ion channels steer neutrophils towards a source of hydrogen peroxide.Template:33927223
33130440 PDF 2020. TRPM2 channel-mediated cell death: An important mechanism linking oxidative stress-inducing pathological factors to associated pathological conditions.Template:33130440
31780732 PDF 2019. Curcumin enhances cisplatin-induced human laryngeal squamous cancer cell death through activation of TRPM2 channel and mitochondrial oxidative stress.Template:31780732
31578243 PDF 2019. Circulating uromodulin inhibits systemic oxidative stress by inactivating the TRPM2 channel.Template:31578243
31250378 PDF 2020. Reversal of Global Ischemia-Induced Cognitive Dysfunction by Delayed Inhibition of TRPM2 Ion Channels.Template:31250378
29463868 PDF 2018. CD38 promotes pristane-induced chronic inflammation and increases susceptibility to experimental lupus by an apoptosis-driven and TRPM2-dependent mechanism.Template:29463868
22847436 PDF 2012. Pore collapse underlies irreversible inactivation of TRPM2 cation channel currents.Template:22847436
22493272 PDF 2012. Redox signal-mediated sensitization of transient receptor potential melastatin 2 (TRPM2) to temperature affects macrophage functions.Template:22493272
21709234 PDF 2011. Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes.Template:21709234
19887679 PDF 2009. In with the TRP channels: intracellular functions for TRPM1 and TRPM2.Template:19887679