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(Created page with "*'''Monoclonal immunoglobulin diseases include light-chain deposition disease, light- and heavy-chain deposition disease, heavy-chain deposition disease, type I cryoglobulinemia, immune tubular glomerulopathy and fibrillar glomerulopathy. In recent years, the spectrum of monoclonal gammopathy has gradually expanded to include tissue deposits of monoisotype Ig but lacks evidence for a circulating monoclonal Ig component.''' *'''fibrillary glomerulopathy, cryoglobulinemia...")
 
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*'''Monoclonal immunoglobulin diseases include light-chain deposition disease, light- and heavy-chain deposition disease,
*''Monoclonal immunoglobulin diseases include light-chain deposition disease, light- and heavy-chain deposition disease,heavy-chain deposition disease, type I cryoglobulinemia, immune tubular glomerulopathy and fibrillar glomerulopathy.
heavy-chain deposition disease, type I cryoglobulinemia, immune tubular glomerulopathy and fibrillar glomerulopathy.
In recent years, the spectrum of monoclonal gammopathy has gradually expanded to include tissue deposits of monoisotype Ig but lacks evidence for a circulating monoclonal Ig component.''
In recent years, the spectrum of monoclonal gammopathy has gradually expanded to include tissue deposits of monoisotype Ig but lacks evidence for a circulating monoclonal Ig component.'''
*''fibrillary glomerulopathy, cryoglobulinemia type 1, membranous glomerulonephritis with IgGκ deposition, light-chain amyloidosis, light- and heavy-chain deposition disease, lupus nephritis, atypical anti-GBM nephritis with IgG deposition and idiopathic MPGN.''
*'''fibrillary glomerulopathy, cryoglobulinemia type 1, membranous
glomerulonephritis with IgGκ deposition, light-chain amyloidosis, light- and heavy-chain deposition disease, lupus
nephritis, atypical anti-GBM nephritis with IgG deposition and idiopathic MPGN.'''
*daratumumab ==anti cd38
*daratumumab ==anti cd38
*0.8% of kidney biopsies
*0.8% of kidney biopsies

Revision as of 16:39, 4 February 2024

  • Monoclonal immunoglobulin diseases include light-chain deposition disease, light- and heavy-chain deposition disease,heavy-chain deposition disease, type I cryoglobulinemia, immune tubular glomerulopathy and fibrillar glomerulopathy.

In recent years, the spectrum of monoclonal gammopathy has gradually expanded to include tissue deposits of monoisotype Ig but lacks evidence for a circulating monoclonal Ig component.

  • fibrillary glomerulopathy, cryoglobulinemia type 1, membranous glomerulonephritis with IgGκ deposition, light-chain amyloidosis, light- and heavy-chain deposition disease, lupus nephritis, atypical anti-GBM nephritis with IgG deposition and idiopathic MPGN.
  • daratumumab ==anti cd38
  • 0.8% of kidney biopsies
  • 20% terminal ki; 90% graft recurrence w early graft loss.
  • nephritic/nphrotic init.
  • no cryoglobulins (dd: cryo-crystalglobulinemic disease)