Pharmacology (TRPM7)

34778271 PDF 2021. Sacubitril Ameliorates Cardiac Fibrosis Through Inhibiting TRPM7 Channel.Template:34778271
34733174 PDF 2021. NSAIDs Naproxen, Ibuprofen, Salicylate, and Aspirin Inhibit TRPM7 Channels by Cytosolic Acidification.Template:34733174
29256407 PDF 2017. Effect of oral magnesium supplementation on the transcription of TRPM6, TRPM7, and SLC41A1 in individuals newly diagnosed of pre-hypertension. A randomized, double-blind, placebo-controlled trial.Template:29256407
24413991 PDF 2014. The effects of Nigella sativa (Ns), Anthemis hyalina (Ah) and Citrus sinensis (Cs) extracts on the replication of coronavirus and the expression of TRP genes family.Template:24413991
33356397 PDF 2021. Magnesium Supplementation Attenuates Pulmonary Hypertension via Regulation of Magnesium Transporters.Template:33356397
29672725 PDF 2019. Down-Regulated Expression of Magnesium Transporter Genes Following a High Magnesium Diet Attenuates Sciatic Nerve Crush Injury.Template:29672725
28636082 PDF 2018. Salvianolic acid B protects against acute lung injury by decreasing TRPM6 and TRPM7 expressions in a rat model of sepsis.Template:28636082
28545665 PDF 2017. AstragalosideⅣ against cardiac fibrosis by inhibiting TRPM7 channel.Template:28545665
28123180 PDF 2017. Magnesium prevents phosphate-induced vascular calcification via TRPM7 and Pit-1 in an aortic tissue culture model.Template:28123180
23934071 PDF 2013. Inhibition of TRPM7 channels prevents proliferation and differentiation of human lung fibroblasts.Template:23934071
18268139 PDF 2008. Downregulation of renal TRPM7 and increased inflammation and fibrosis in aldosterone-infused mice: effects of magnesium.Template:18268139
38162115 PDF 2024. Cannabigerolic Acid (CBGA) Inhibits the TRPM7 Ion Channel Through its Kinase Domain.Template:38162115
37943249 PDF 2024. Analogs of FTY720 inhibit TRPM7 but not S1PRs and exert multimodal anti-inflammatory effects.Template:37943249
37786778 PDF 2023. Inactivation of TRPM7 Kinase Targets AKT Signaling and Cyclooxygenase-2 Expression in Human CML Cells.Template:37786778
37662207 PDF 2023. Novel TRPM7 inhibitors with potent anti-inflammatory effects in vivo.Template:37662207
37328275 PDF 2023. Drugs acting at TRPM7 channels inhibit seizure-like activity.Template:37328275
37192136 PDF 2023. Total Syntheses of (+)-Waixenicin A, (+)-9-Deacetoxy-14,15-deepoxyxeniculin, and (-)-Xeniafaraunol A.Template:37192136
37072467 PDF 2023. CBGA ameliorates inflammation and fibrosis in nephropathy.Template:37072467
36705408 PDF 2023. Sevoflurane participates in the protection of rat renal ischemia-reperfusion injury by down-regulating the expression of TRPM7.Template:36705408
36430333 PDF 2022. Carvacrol Inhibits Expression of Transient Receptor Potential Melastatin 7 Channels and Alleviates Zinc Neurotoxicity Induced by Traumatic Brain Injury.Template:36430333
36030694 PDF 2022. Pharmacological agents selectively acting on the channel moieties of TRPM6 and TRPM7.Template:36030694
35917680 PDF 2022. TRPM7 channel inhibition attenuates rheumatoid arthritis articular chondrocyte ferroptosis by suppression of the PKCalpha-NOX4 axis.Template:35917680
35531206 PDF 2022. Melatonin attenuates cerebral hypoperfusion-induced hippocampal damage and memory deficits in rats by suppressing TRPM7 channels.Template:35531206
35406741 PDF 2022. Neuroprotective Effects of TRPM7 Deletion in Parvalbumin GABAergic vs. Glutamatergic Neurons following Ischemia.Template:35406741
34285910 PDF 2021. Oridonin Promotes Apoptosis and Restrains the Viability and Migration of Bladder Cancer by Impeding TRPM7 Expression via the ERK and AKT Signaling Pathways.Template:34285910
33993722 PDF 2021. Pharmacological and Genetic Blockade of Trpm7 in the Carotid Body Treats Obesity-Induced Hypertension.Template:33993722
33927631 PDF 2021. Blockade of TRPM7 Alleviates Chondrocyte Apoptosis and Articular Cartilage Damage in the Adjuvant Arthritis Rat Model Through Regulation of the Indian Hedgehog Signaling Pathway.Template:33927631
33891828 PDF 2021. Leptin Induces Epigenetic Regulation of Transient Receptor Potential Melastatin 7 in Rat Adrenal Pheochromocytoma Cells.Template:33891828
33691194 PDF 2021. Substantial involvement of TRPM7 inhibition in the therapeutic effect of Ophiocordyceps sinensis on pulmonary hypertension.Template:33691194
33435261 PDF 2021. Lidocaine Suppresses Viability and Migration of Human Breast Cancer Cells: TRPM7 as a Target for Some Breast Cancer Cell Lines.Template:33435261
33310045 PDF 2021. Carvacrol affects breast cancer cells through TRPM7 mediated cell cycle regulation.Template:33310045
33293462 PDF 2020. Targeting the ion channel TRPM7 promotes the thymic development of regulatory T cells by promoting IL-2 signaling.Template:33293462
33114331 PDF 2020. The Transient Receptor Potential Melastatin 7 (TRPM7) Inhibitors Suppress Seizure-Induced Neuron Death by Inhibiting Zinc Neurotoxicity.Template:33114331
33029295 PDF 2020. Inhibition of transient receptor potential melastatin 7 (TRPM7) protects against Schwann cell trans-dedifferentiation and proliferation during Wallerian degeneration.Template:33029295
33028185 PDF 2020. TRPM7 silencing attenuates Mg(2+) influx in cardiac myoblasts, H9c2 cells.Template:33028185
32994545 PDF 2020. Waixenicin A, a marine-derived TRPM7 inhibitor: a promising CNS drug lead.Template:32994545
32977698 PDF 2020. Mapping TRPM7 Function by NS8593.Template:32977698
37837806 PDF 2023. Improvement of actin dynamics and cognitive impairment in diabetes through troxerutin-mediated downregulation of TRPM7/CaN/cofilin.Template:37837806
37495546 PDF 2023. Sinomenine regulates circTRPM7-related pathway to inhibit gastric cancer cell growth and metastasis.Template:37495546
37208975 PDF 2023. Downregulation of TRPM7, TRPM8, and TRPV1 channels modulate apoptotic parameters and neurodegenerative markers: Focus on neuronal differentiation and Parkinson's disease model.Template:37208975
37142088 PDF 2023. Carvacrol enhances anti-tumor activity and mitigates cardiotoxicity of sorafenib in thioacetamide-induced hepatocellular carcinoma model through inhibiting TRPM7.Template:37142088
36567422 PDF 2023. Involvement of TRPM7 Channel on the Induction of Diabetic Neuropathic Pain in Mice: Protective Role of Selenium and Curcumin.Template:36567422
35940237 PDF 2022. Transient receptor potential melastatin 7 and their modulators.Template:35940237
35850880 PDF 2023. Overexpression of TRPM7 promotes the therapeutic effect of curcumin in wound healing through the STAT3/SMAD3 signaling pathway in human fibroblasts.Template:35850880
35277895 PDF 2022. Inhibition of TRPM7 with carvacrol suppresses glioblastoma functions in vivo.Template:35277895
35171694 PDF 2022. Suppression of Transient Receptor Potential Melastatin 7 by Carvacrol Protects against Injured Spinal Cord by Inhibiting Blood-Spinal Cord Barrier Disruption.Template:35171694
35099165 PDF 2022. Unraveling the Cardiac Effects Induced by Carvacrol in Spontaneously Hypertensive Rats: Involvement of Transient Receptor Potential Melastatin Subfamily 4 and 7 Channels.Template:35099165
34958137 PDF 2022. Suppression of transient receptor potential melastatin 7 regulates pluripotency, proliferation, and differentiation of mouse embryonic stem cells via mechanistic target of rapamycin-extracellular signal-regulated kinase activation.Template:34958137
34953296 PDF 2022. Modulators of TRPM7 and its potential as a drug target for brain tumours.Template:34953296
34752845 PDF 2022. Stimulating TRPM7 suppresses cancer cell proliferation and metastasis by inhibiting autophagy.Template:34752845
34559972 PDF 2022. Cardioprotective effect of fingolimod against calcium paradox-induced myocardial injury in the isolated rat heart.Template:34559972
34103198 PDF 2022. New use of old medicine: Nifedipine acts on the TRP family and inflammatory proteins in the treatment of chilblain.Template:34103198
33989904 PDF 2021. CCT128930 is a novel and potent antagonist of TRPM7 channel.Template:33989904
33970850 PDF 2021. Carvacrol as a Potential Neuroprotective Agent for Neurological Diseases: A Systematic Review Article.Template:33970850
33647257 PDF 2021. Carvacrol alleviates liver fibrosis by inhibiting TRPM7 and modulating the MAPK signaling pathway.Template:33647257
33143990 PDF 2021. Panax Notoginseng Saponins suppresses TRPM7 via the PI3K/AKT pathway to inhibit hypertrophic scar formation in vitro.Template:33143990
33080445 PDF 2020. Inhibition of TRPM7 with waixenicin A reduces glioblastoma cellular functions.Template:33080445
32924998 PDF 2021. Protective effect of inhibiting TRPM7 expression on hypoxia post-treatment H9C2 cardiomyocytes.Template:32924998
32468675 PDF 2020. Suppression of TRPM7 enhances TRAIL-induced apoptosis in triple-negative breast cancer cells.Template:32468675
31848974 PDF 2020. Carvacrol effectively protects demyelination by suppressing transient receptor potential melastatin 7 (TRPM7) in Schwann cells.Template:31848974
31844251 PDF 2020. Inhibition of TRPM7 blocks MRTF/SRF-dependent transcriptional and tumorigenic activity.Template:31844251
31739105 PDF 2020. Astragaloside IV inhibits cardiac fibrosis via miR-135a-TRPM7-TGF-beta/Smads pathway.Template:31739105
31640089 PDF 2019. TRPM7 deficiency suppresses cell proliferation, migration, and invasion in human colorectal cancer via regulation of epithelial-mesenchymal transition.Template:31640089
30952425 PDF 2019. The simultaneous downregulation of TRPM7 and MagT1 in human mesenchymal stem cells in vitro: Effects on growth and osteogenic differentiation.Template:30952425
30678852 PDF 2019. Aldosterone and Ion Channels.Template:30678852
30513244 PDF 2019. Effects of Salivary Mg on Head and Neck Carcinoma via TRPM7.Template:30513244
29383689 PDF 2018. Magnesium Reduces Blood-Brain Barrier Permeability and Regulates Amyloid-beta Transcytosis.Template:29383689
28860220 PDF 2017. Interleukin-18 Enhances Vascular Calcification and Osteogenic Differentiation of Vascular Smooth Muscle Cells Through TRPM7 Activation.Template:28860220
28736242 PDF 2018. Suppression of cortical TRPM7 protein attenuates oxidative damage after traumatic brain injury via Akt/endothelial nitric oxide synthase pathway.Template:28736242
28573641 PDF 2017. Downregulation of TRPM7 suppressed migration and invasion by regulating epithelial-mesenchymal transition in prostate cancer cells.Template:28573641
28526576 PDF 2017. Carvacrol promotes neuroprotection in the mouse hemiparkinsonian model.Template:28526576
28393175 PDF 2017. TRPM7 channels mediate the functional changes in cardiac fibroblasts induced by angiotensin II.Template:28393175
32945378 PDF 2020. Gallium ions promote osteoinduction of human and mouse osteoblasts via the TRPM7/Akt signaling pathway.Template:32945378
32907556 PDF 2020. Knockdown of TRPM7 prevents tumor growth, migration, and invasion through the Src, Akt, and JNK pathway in bladder cancer.Template:32907556
32706027 PDF 2020. Epidermal growth factor signaling through transient receptor potential melastatin 7 cation channel regulates vascular smooth muscle cell function.Template:32706027
32390858 PDF 2020. Isoproterenol-Dependent Activation of TRPM7 Protects Against Neurotoxin-Induced Loss of Neuroblastoma Cells.Template:32390858
32337263 PDF 2020. Effect of Carvacrol, TRP Channels Modulator, on Cardiac Electrical Activity.Template:32337263
32215176 PDF 2020. Suppression of TRPM7 Inhibited Hypoxia-Induced Migration and Invasion of Androgen-Independent Prostate Cancer Cells by Enhancing RACK1-Mediated Degradation of HIF-1alpha.Template:32215176
31947967 PDF 2020. The Role of Transient Receptor Potential Melastatin 7 (TRPM7) in Cell Viability: A Potential Target to Suppress Breast Cancer Cell Cycle.Template:31947967
31697634 PDF 2019. Leptin Activates Trpm7 Channels in the Carotid Body As a Mechanism of Obesity-Related Hypertension.Template:31697634
31559137 PDF 2019. Magnesium Regulates Endothelial Barrier Functions through TRPM7, MagT1, and S1P1.Template:31559137
31545149 PDF 2019. Leptin Induces Hypertension Acting on Transient Receptor Potential Melastatin 7 Channel in the Carotid Body.Template:31545149
31219801 PDF 2019. TRPM7 channel inhibition exacerbates pulmonary arterial hypertension through MEK/ERK pathway.Template:31219801
30486272 PDF 2018. Carvacrol Attenuates Hippocampal Neuronal Death after Global Cerebral Ischemia via Inhibition of Transient Receptor Potential Melastatin 7.Template:30486272
29984342 PDF 2018. Down-regulation of transient receptor potential melastatin member 7 prevents migration and invasion of renal cell carcinoma cells via inactivation of the Src and Akt pathway.Template:29984342
29615639 PDF 2018. TRPM7 in CHBP-induced renoprotection upon ischemia reperfusion-related injury.Template:29615639
29108260 PDF 2017. Angiotensin-converting enzyme-2 overexpression improves atrial electrical remodeling through TRPM7 signaling pathway.Template:29108260
29047214 PDF 2018. Tanshinone IIA alleviates lipopolysaccharide-induced acute lung injury by downregulating TRPM7 and pro-inflammatory factors.Template:29047214
28810912 PDF 2017. Inhibition of TRPM7 suppresses cell proliferation of colon adenocarcinoma in vitro and induces hypomagnesemia in vivo without affecting azoxymethane-induced early colon cancer in mice.Template:28810912
28533887 PDF 2017. Lidocaine suppresses glioma cell proliferation by inhibiting TRPM7 channels.Template:28533887
28356194 PDF 2017. Assessment of TRPM7 functions by drug-like small molecules.Template:28356194
28161478 PDF 2017. Identification of TG100-115 as a new and potent TRPM7 kinase inhibitor, which suppresses breast cancer cell migration and invasion.Template:28161478
27693494 PDF 2016. Bradykinin promotes migration and invasion of hepatocellular carcinoma cells through TRPM7 and MMP2.Template:27693494
27629139 PDF 2016. TRPM7 channel inhibition mediates midazolam-induced proliferation loss in human malignant glioma.Template:27629139
27614570 PDF 2016. Aripiprazole inhibits polyI:C-induced microglial activation possibly via TRPM7.Template:27614570
26669310 PDF 2016. Mibefradil represents a new class of benzimidazole TRPM7 channel agonists.Template:26669310

26268950 PDF 2015. Angiotensin II prevents calcification in vascular smooth muscle cells by enhancing magnesium influx.'

26220904 PDF 2015. Carvacrol attenuates traumatic neuronal injury through store-operated Ca(2+) entry-independent regulation of intracellular Ca(2+) homeostasis.Template:26220904
26164719 PDF 2015. Inhibition of TRPM7 Attenuates Rat Aortic Smooth Muscle Cell Proliferation Induced by Angiotensin II: Role of Genistein.Template:26164719
25863514 PDF 2015. Effects of laser irradiation at different wavelengths (660, 810, 980, and 1064 nm) on transient receptor potential melastatin channels in an animal model of wound healing.Template:25863514
25450695 PDF 2014. EGF stimulates Mg(2+) influx in mammary epithelial cells.Template:25450695
25053832 PDF 2014. CD147 up-regulates calcium-induced chemotaxis, adhesion ability and invasiveness of human neutrophils via a TRPM-7-mediated mechanism.Template:25053832
28410232 PDF 2017. Vacquinol-1 inducible cell death in glioblastoma multiforme is counter regulated by TRPM7 activity induced by exogenous ATP.Template:28410232
28129376 PDF 2017. Modulation of Human Cardiac TRPM7 Current by Extracellular Acidic pH Depends upon Extracellular Concentrations of Divalent Cations.Template:28129376
28084627 PDF 2017. Carvacrol after status epilepticus (SE) prevents recurrent SE, early seizures, cell death, and cognitive decline.Template:28084627
28061441 PDF 2017. Activation of TRPM7 by naltriben enhances migration and invasion of glioblastoma cells.Template:28061441
27803760 PDF 2016. Carvacrol Alleviates Prostate Cancer Cell Proliferation, Migration, and Invasion through Regulation of PI3K/Akt and MAPK Signaling Pathways.Template:27803760
27662662 PDF 2016. Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway.Template:27662662
27466368 PDF 2016. Aldosterone Upregulates Transient Receptor Potential Melastatin 7 (TRPM7).Template:27466368
27010689 PDF 2016. Regulation of TRPM7 Function by IL-6 through the JAK2-STAT3 Signaling Pathway.Template:27010689
26928801 PDF 2016. Transient Receptor Potential Melastatin 7 Cation Channel Kinase: New Player in Angiotensin II-Induced Hypertension.Template:26928801
26671672 PDF 2015. Hepatocystin is Essential for TRPM7 Function During Early Embryogenesis.Template:26671672
24647664 PDF 2014. Quercetin induces apoptosis by inhibiting MAPKs and TRPM7 channels in AGS cells.Template:24647664
24633576 PDF 2014. Activation of TRPM7 channels by small molecules under physiological conditions.Template:24633576
24631962 PDF 2014. Mycelia glycoproteins from Cordyceps sobolifera ameliorate cyclosporine-induced renal tubule dysfunction in rats.Template:24631962
24507022 PDF 2014. Effect of verapamil and lidocaine on TRPM and NaV1.9 gene expressions in renal ischemia-reperfusion.Template:24507022
24258314 PDF 2014. Suppression of renal TRPM7 may alleviate kidney injury in the renal transplantation.Template:24258314
24220678 PDF 2014. Blockage of TRPM7 channel induces hepatic stellate cell death through endoplasmic reticulum stress-mediated apoptosis.Template:24220678
24138320 PDF 2014. The effect of TRPM7 suppression on the proliferation, migration and osteogenic differentiation of human dental pulp stem cells.Template:24138320
23432067 PDF 2013. TRP channels as therapeutic targets in kidney disease and hypertension.Template:23432067
22896586 PDF 2012. Upregulation of TRPM7 channels by angiotensin II triggers phenotypic switching of vascular smooth muscle cells of ascending aorta.Template:22896586
22406504 PDF 2012. Inhibition of transient receptor potential melastain 7 channel increases HSCs apoptosis induced by TRAIL.Template:22406504
22231470 PDF 2012. Ginsenoside-Rd attenuates TRPM7 and ASIC1a but promotes ASIC2a expression in rats after focal cerebral ischemia.Template:22231470
22183257 PDF 2012. Silencing TRPM7 mimics the effects of magnesium deficiency in human microvascular endothelial cells.Template:22183257
21978419 PDF 2011. EGF enhances the migration of cancer cells by up-regulation of TRPM7.Template:21978419
19734892 PDF 2009. Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia.Template:19734892
19145781 PDF 2009. Regulation of the novel Mg2+ transporter transient receptor potential melastatin 7 (TRPM7) cation channel by bradykinin in vascular smooth muscle cells.Template:19145781
18395621 PDF 2008. TrkA pathway(s) is involved in regulation of TRPM7 expression in hippocampal neurons subjected to ischemic-reperfusion and oxygen-glucose deprivation.Template:18395621
26136930 PDF 2015. Effects of angiotensin II on transient receptor potential melastatin 7 channel function in cardiac fibroblasts.Template:26136930
26028116 PDF 2015. Inhibition of Transient Receptor Potential Melastain 7 Enhances Apoptosis Induced by TRAIL in PC-3 cells.Template:26028116
25965832 PDF 2015. Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion.Template:25965832
25913706 PDF 2015. Xyloketal B suppresses glioblastoma cell proliferation and migration in vitro through inhibiting TRPM7-regulated PI3K/Akt and MEK/ERK signaling pathways.Template:25913706
25799367 PDF 2015. Silencing TRPM7 in mouse cortical astrocytes impairs cell proliferation and migration via ERK and JNK signaling pathways.Template:25799367
25761704 PDF 2015. TRPM7 inhibitor carvacrol protects brain from neonatal hypoxic-ischemic injury.Template:25761704
25438992 PDF 2015. Suppression of TRPM7 inhibits proliferation, migration, and invasion of malignant human glioma cells.Template:25438992
25437439 PDF 2014. Natural and Synthetic Modulators of the TRPM7 Channel.Template:25437439
25426416 PDF 2014. MycN promotes TRPM7 expression and cell migration in neuroblastoma through a process that involves polyamines.Template:25426416
25277194 PDF 2014. N-Myc-induced up-regulation of TRPM6/TRPM7 channels promotes neuroblastoma cell proliferation.Template:25277194
25169754 PDF 2015. Local anesthetic lidocaine inhibits TRPM7 current and TRPM7-mediated zinc toxicity.Template:25169754
24995695 PDF 2014. Inhibition of TRPM7 channels reduces degranulation and release of cytokines in rat bone marrow-derived mast cells.Template:24995695
24992702 PDF 2014. Spongiapyridine and related spongians isolated from an Indonesian Spongia sp.Template:24992702
24817288 PDF 2014. Influence of lactuside B on the expression of AQP4 and TRPM7 mRNAs in the cerebral cortex after cerebral ischemia injury.Template:24817288
24769209 PDF 2014. Cholesterol-induced activation of TRPM7 regulates cell proliferation, migration, and viability of human prostate cells.Template:24769209
24223965 PDF 2013. Role of TRPM7 channels in hyperglycemia-mediated injury of vascular endothelial cells.Template:24223965
25780674 PDF 2013. Buxus Microphylla var. Koreana Nakai Extract for the Treatment of Gastric Cancer.Template:25780674
23838006 PDF 2013. Aldosterone signaling through transient receptor potential melastatin 7 cation channel (TRPM7) and its alpha-kinase domain.Template:23838006
28664056 PDF 2013. Involvement of transient receptor potential melastatin type 7 channels on Poncirus fructus-induced depolarizations of pacemaking activity in interstitial cells of Cajal from murine small intestine.Template:28664056
25780669 PDF 2013. Effects of Ulmi Pumilae Cortex on AGS Gastric Cancer Cells.Template:25780669
23717173 PDF 2013. Involvement of melastatin type transient receptor potential 7 channels in ginsenoside Rd-induced apoptosis in gastric and breast cancer cells.Template:23717173
23471296 PDF 2013. TRPM7 is regulated by halides through its kinase domain.Template:23471296
23426784 PDF 2013. Inhibition of cancer cell proliferation by midazolam by targeting transient receptor potential melastatin 7.Template:23426784
23421680 PDF 2013. trans-Resveratrol protects ischemic PC12 Cells by inhibiting the hypoxia associated transcription factors and increasing the levels of antioxidant defense enzymes.Template:23421680
7108782 PDF 1982. Calcium and the action of adrenaline, adenosine triphosphate and carbachol on guinea-pig taenia caeci.Template:7108782
18026717 PDF 2008. Down-regulation of TRPM6-mediated magnesium influx by cyclosporin A.Template:18026717
17904584 PDF 2007. Electroacupuncture regulates TRPM7 expression through the trkA/PI3K pathway after cerebral ischemia-reperfusion in rats.Template:17904584
17482355 PDF 2007. NGF-induced reduction of an outward-rectifying TRPM7-like current in rat CA1 hippocampal neurons.Template:17482355
17479281 PDF 2007. Regulation of transient receptor potential (TRP) channels by phosphoinositides.Template:17479281
16201261 PDF 2005. Effect of electroacupuncture on TRPM7 mRNA expression after cerebral ischemia/reperfusion in rats via TrkA pathway.Template:16201261
15591230 PDF 2005. Transient receptor potential melastatin 7 ion channels regulate magnesium homeostasis in vascular smooth muscle cells: role of angiotensin II.Template:15591230
23168410 PDF 2013. Increase in serum Ca2+/Mg2+ ratio promotes proliferation of prostate cancer cells by activating TRPM7 channels.Template:23168410
23145923 PDF 2013. Sphingosine and FTY720 are potent inhibitors of the transient receptor potential melastatin 7 (TRPM7) channels.Template:23145923
23047499 PDF 2012. Retrovirus-mediated siRNA targeting TRPM7 gene induces apoptosis in RBL-2H3 cells.Template:23047499
22974787 PDF 2012. Differential effects of cyclosporin A and tacrolimus on magnesium influx in Caco2 cells.Template:22974787
25780645 PDF 2012. Involvement of Transient Receptor Potential Melastatin 7 Channels in Sophorae Radix-induced Apoptosis in Cancer Cells: Sophorae Radix and TRPM7.Template:25780645
22922232 PDF 2012. 2-aminoethyl diphenyl borinate (2-APB) inhibits TRPM7 channels through an intracellular acidification mechanism.Template:22922232
22901271 PDF 2013. The role of waixenicin A as transient receptor potential melastatin 7 blocker.Template:22901271
22820907 PDF 2013. Current understanding of TRPM7 pharmacology and drug development for stroke.Template:22820907
22350744 PDF 2012. Effects of ginsenoside on pacemaker potentials of cultured interstitial cells of Cajal clusters from the small intestine of mice.Template:22350744
22242975 PDF 2012. Natural and synthetic modulators of SK (K(ca)2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7.Template:22242975
22166235 PDF 2012. Targeted silencing of TRPM7 ion channel induces replicative senescence and produces enhanced cytotoxicity with gemcitabine in pancreatic adenocarcinoma.Template:22166235
22102510 PDF 2012. Modulation of transient receptor potential melastatin related 7 channel by presenilins.Template:22102510
21926172 PDF 2011. Waixenicin A inhibits cell proliferation through magnesium-dependent block of transient receptor potential melastatin 7 (TRPM7) channels.Template:21926172
21867724 PDF 2012. Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases.Template:21867724
21607648 PDF 2011. Effects of transient receptor potential channel blockers on pacemaker activity in interstitial cells of Cajal from mouse small intestine.Template:21607648
21552293 PDF 2011. TRPM7 in cerebral ischemia and potential target for drug development in stroke.Template:21552293
21487014 PDF 2011. Hypoxia induces an increase in intracellular magnesium via transient receptor potential melastatin 7 (TRPM7) channels in rat hippocampal neurons in vitro.Template:21487014
21443732 PDF 2011. Transient receptor potential melastatin 7 channels are involved in ginsenoside Rg3-induced apoptosis in gastric cancer cells.Template:21443732
21122141 PDF 2010. The modulation of TRPM7 currents by nafamostat mesilate depends directly upon extracellular concentrations of divalent cations.Template:21122141
20567598 PDF 2010. Blockade of TRPM7 channel activity and cell death by inhibitors of 5-lipoxygenase.Template:20567598
20413646 PDF 2010. Development and optimization of a high-throughput bioassay for TRPM7 ion channel inhibitors.Template:20413646
20180991 PDF 2010. Conformational preference of ChaK1 binding peptides: a molecular dynamics study.Template:20180991
20068131 PDF 2010. High glucose-induced oxidative stress increases transient receptor potential channel expression in human monocytes.Template:20068131
19454490 PDF 2009. Silencing TRPM7 promotes growth/proliferation and nitric oxide production of vascular endothelial cells via the ERK pathway.Template:19454490
19271420 PDF 2008. Dietary inulin in mice stimulates Mg2+ absorption and modulates TRPM6 and TRPM7 expression in large intestine and kidney.Template:19271420
19135721 PDF 2009. Carvacrol is a novel inhibitor of Drosophila TRPL and mammalian TRPM7 channels.Template:19135721
19032368 PDF 2008. Suppression of transient receptor potential melastatin 7 channel induces cell death in gastric cancer.Template:19032368
18799634 PDF 2009. Bradykinin regulates calpain and proinflammatory signaling through TRPM7-sensitive pathways in vascular smooth muscle cells.Template:18799634
17510191 PDF 2007. TRPM7 channel is sensitive to osmotic gradients in human kidney cells.Template:17510191
36614214 PDF 2023. Amelioration of Cyclosporine A-Induced Acute Nephrotoxicity by Cordyceps cicadae Mycelia via Mg(+2) Reabsorption and the Inhibition of GRP78-IRE1-CHOP Pathway: In Vivo and In Vitro.Template:36614214
35385223 PDF 2022. Fibroblast growth factor-23 and parathyroid hormone suppress small intestinal magnesium absorption.Template:35385223
34950031 PDF 2021. Mechanisms of Cancer Inhibition by Local Anesthetics.Template:34950031
17095511 PDF 2007. Activation of TRPM7 channels by phospholipase C-coupled receptor agonists.Template:17095511
16109804 PDF 2006. Differential regulation of transient receptor potential melastatin 6 and 7 cation channels by ANG II in vascular smooth muscle cells from spontaneously hypertensive rats.Template:16109804
29672308 PDF 2018. Modulation of Pacemaker Potentials in Murine Small Intestinal Interstitial Cells of Cajal by Gamisoyo-San, a Traditional Chinese Herbal Medicine.Template:29672308
37773101 PDF 2023. Antibacterial and anti-corona virus (229E) activity of Nigella sativa oil combined with photodynamic therapy based on methylene blue in wound infection: in vitro and in vivo study.Template:37773101
37057101 PDF 2023. The history and mystery of sacubitril/valsartan: From clinical trial to the real world.Template:37057101
36479630 PDF 2023. The impact of sacubitril/valsartan on outcome in patients suffering from heart failure with a concomitant diabetes mellitus.Template:36479630
36348778 PDF 2022. Therapeutic application of carvacrol: A comprehensive review.Template:36348778
35141300 PDF 2022. Serum Calcification Propensity and Calcification of the Abdominal Aorta in Patients With Primary Aldosteronism.Template:35141300

34093778 PDF 2021. Potential role of Nigella sativa supplementation with physical activity in prophylaxis and treatment of COVID-19: a contemporary review.'

34064039 PDF 2021. The Molecular Basis of COVID-19 Pathogenesis, Conventional and Nanomedicine Therapy.Template:34064039
37493767 PDF 2023. Astragaloside IV alleviates lung inflammation in Klebsiella pneumonia rats by suppressing TGF-beta1/Smad pathway.Template:37493767
36747205 PDF 2023. Empagliflozin suppressed cardiac fibrogenesis through sodium-hydrogen exchanger inhibition and modulation of the calcium homeostasis.Template:36747205
35782773 PDF 2022. Neuroprotective effects of carvacrol against Alzheimer's disease and other neurodegenerative diseases: A review.Template:35782773
35454101 PDF 2022. Insights into Recent Studies on Biotransformation and Pharmacological Activities of Ginsenoside Rd.Template:35454101
35204269 PDF 2022. The Beneficial Effect of Carvacrol in HL-1 Cardiomyocytes Treated with LPS-G: Anti-Inflammatory Pathway Investigations.Template:35204269
32393384 PDF 2020. Effect of long-term treatment of Carvacrol on glucose metabolism in Streptozotocin-induced diabetic mice.Template:32393384
31672270 PDF 2019. Interfacial Binding Sites for Cholesterol on TRP Ion Channels.Template:31672270
30876463 PDF 2019. Lidocaine inhibits growth, migration and invasion of gastric carcinoma cells by up-regulation of miR-145.Template:30876463
26592517 PDF 2015. Carvacrol protects neuroblastoma SH-SY5Y cells against Fe(2+)-induced apoptosis by suppressing activation of MAPK/JNK-NF-kappaB signaling pathway.Template:26592517
24926802 PDF 2014. Transient receptor potential channels as targets for phytochemicals.Template:24926802
21159786 PDF 2011. Magnesium supplementation, metabolic and inflammatory markers, and global genomic and proteomic profiling: a randomized, double-blind, controlled, crossover trial in overweight individuals.Template:21159786
37854719 PDF 2023. Effect of Astragaloside IV on improving cardiac function in rats with heart failure: a preclinical systematic review and meta-analysis.Template:37854719
37426627 PDF 2023. Untapping the Potential of Astragaloside IV in the Battle Against Respiratory Diseases.Template:37426627
37251311 PDF 2023. Review on the protective mechanism of astragaloside IV against cardiovascular diseases.Template:37251311
37138582 PDF 2023. Integrating Network Pharmacology and Experimental Validation to Explore the Pharmacological Mechanism of Astragaloside IV in Treating Bleomycin-Induced Pulmonary Fibrosis.Template:37138582
36844925 PDF 2022. On the modulation of TRPM channels: Current perspectives and anticancer therapeutic implications.Template:36844925
36814491 PDF 2023. Renal function protection and the mechanism of ginsenosides: Current progress and future perspectives.Template:36814491
36744251 PDF 2023. Traditional Chinese medicine for treatment of sepsis and related multi-organ injury.Template:36744251

36741996 PDF 2022. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.'

36567278 PDF 2023. Neuroprotective Potential and Underlying Pharmacological Mechanism of Carvacrol for Alzheimer's and Parkinson's Diseases.Template:36567278
36408254 PDF 2022. Astragalus and its formulas as a therapeutic option for fibrotic diseases: Pharmacology and mechanisms.Template:36408254
36160396 PDF 2022. Astragalus Mongholicus: A review of its anti-fibrosis properties.Template:36160396
36033133 PDF 2022. Ginsenoside Rd Promotes Cardiac Repair After Myocardial Infarction by Modulating Monocytes/Macrophages Subsets Conversion.Template:36033133
35928281 PDF 2022. Biotransformation, Pharmacokinetics, and Pharmacological Activities of Ginsenoside Rd Against Multiple Diseases.Template:35928281
35873557 PDF 2022. A Review of Neuroprotective Effects and Mechanisms of Ginsenosides From Panax Ginseng in Treating Ischemic Stroke.Template:35873557
35656031 PDF 2022. Astragaloside IV Ameliorates Isoprenaline-Induced Cardiac Fibrosis in Mice via Modulating Gut Microbiota and Fecal Metabolites.Template:35656031
34811833 PDF 2022. Sorafenib attenuates liver fibrosis by triggering hepatic stellate cell ferroptosis via HIF-1alpha/SLC7A11 pathway.Template:34811833
34594406 PDF 2021. Se alleviates homocysteine-induced fibrosis in cardiac fibroblasts via downregulation of lncRNA MEG3.Template:34594406
34408981 PDF 2021. Perioperative Intravenous Lidocaine and Metastatic Cancer Recurrence - A Narrative Review.Template:34408981
34277971 PDF 2021. Canagliflozin, serum magnesium and cardiovascular outcomes-Analysis from the CANVAS Program.Template:34277971
33866775 PDF 2021. Lobeglitazone: A Novel Thiazolidinedione for the Management of Type 2 Diabetes Mellitus.Template:33866775
33163084 PDF 2020. Carvacrol: An In Silico Approach of a Candidate Drug on HER2, PI3Kalpha, mTOR, hER-alpha, PR, and EGFR Receptors in the Breast Cancer.Template:33163084
32982178 PDF 2020. Astragaloside IV: An Effective Drug for the Treatment of Cardiovascular Diseases.Template:32982178
32766241 PDF 2020. Repositioning Lidocaine as an Anticancer Drug: The Role Beyond Anesthesia.Template:32766241
31903884 PDF 2020. Selenium and Neurological Diseases: Focus on Peripheral Pain and TRP Channels.Template:31903884
28706559 PDF 2017. Insights into the Roles of Midazolam in Cancer Therapy.Template:28706559
28197834 PDF 2017. Effects of Canagliflozin on Serum Magnesium in Patients With Type 2 Diabetes Mellitus: A Post Hoc Analysis of Randomized Controlled Trials.Template:28197834
28123510 PDF 2017. Effects of Prunus mume Siebold & Zucc. in the pacemaking activity of interstitial cells of Cajal in murine small intestine.Template:28123510
27630732 PDF 2016. A Role of Ginseng and Its Constituents in the Treatment of Central Nervous System Disorders.Template:27630732
26236231 PDF 2015. Protective effects of ginseng on neurological disorders.Template:26236231
19305789 PDF 2008. Herbal compounds and toxins modulating TRP channels.Template:19305789
36614214 PDF 2023. Amelioration of Cyclosporine A-Induced Acute Nephrotoxicity by Cordyceps cicadae Mycelia via Mg(+2) Reabsorption and the Inhibition of GRP78-IRE1-CHOP Pathway: In Vivo and In Vitro.Template:36614214
36277193 PDF 2022. Ion channels as a therapeutic target for renal fibrosis.Template:36277193
35685622 PDF 2022. A Review on the Role of TRP Channels and Their Potential as Drug Targets_An Insight Into the TRP Channel Drug Discovery Methodologies.Template:35685622
35345405 PDF 2022. Ileum transcriptional response to prolonged supplementation with phytogenic product containing menthol, carvacrol and carvone.Template:35345405
34950031 PDF 2021. Mechanisms of Cancer Inhibition by Local Anesthetics.Template:34950031
34887769 PDF 2021. Antioxidant Activity, Molecular Docking, Quantum Studies and In Vivo Antinociceptive Activity of Sulfonamides Derived From Carvacrol.Template:34887769
34305611 PDF 2021. Antitumor Effects of Carvacrol and Thymol: A Systematic Review.Template:34305611
32641948 PDF 2019. Carvacrol Ameliorates Pathological Cardiac Hypertrophy in Both In-vivo and In-vitro Models.Template:32641948
31572181 PDF 2019. Carvacrol Attenuates Diabetic Cardiomyopathy by Modulating the PI3K/AKT/GLUT4 Pathway in Diabetic Mice.Template:31572181
29992053 PDF 2018. Beneficial Role of Mg(2+) in Prevention and Treatment of Hypertension.Template:29992053
28508457 PDF 2017. Effects of canagliflozin on cardiovascular risk factors in patients with type 2 diabetes mellitus.Template:28508457
23717153 PDF 2013. A comprehensive review of the therapeutic and pharmacological effects of ginseng and ginsenosides in central nervous system.Template:23717153
37836507 PDF 2023. Vitamins and Minerals for Blood Pressure Reduction in the General, Normotensive Population: A Systematic Review and Meta-Analysis of Six Supplements.Template:37836507
37630371 PDF 2023. Pharmacological Effects of Astragaloside IV: A Review.Template:37630371
36983900 PDF 2023. Attenuation of Endoplasmic Reticulum Stress Enhances Carvacrol-Induced Apoptosis in Osteosarcoma Cell Lines.Template:36983900
36983900 PDF 2023. Attenuation of Endoplasmic Reticulum Stress Enhances Carvacrol-Induced Apoptosis in Osteosarcoma Cell Lines.Template:36983900
36771254 PDF 2023. Magnesium Administration in Chronic Kidney Disease.Template:36771254
34989943 PDF 2022. A novel antagonist of TRPM2 and TRPV4 channels: Carvacrol.Template:34989943
34836340 PDF 2021. Effect of Dapagliflozin and Magnesium Supplementation on Renal Magnesium Handling and Magnesium Homeostasis in Metabolic Syndrome.Template:34836340
34620219 PDF 2021. Astragaloside positively regulated osteogenic differentiation of pre-osteoblast MC3T3-E1 through PI3K/Akt signaling pathway.Template:34620219
34526696 PDF 2022. Advances in TRP channel drug discovery: from target validation to clinical studies.Template:34526696
33537820 PDF 2021. Astragaloside IV improves angiogenesis under hypoxic conditions by enhancing hypoxia‑inducible factor‑1alpha SUMOylation.Template:33537820
23708230 PDF 2013. Carvacrol: from ancient flavoring to neuromodulatory agent.Template:23708230
22994850 PDF 2012. Carvacrol together with TRPC1 elimination improve functional recovery after traumatic brain injury in mice.Template:22994850
36959464 PDF 2023. Satureja khuzistanica Jamzad essential oil and pure carvacrol attenuate TBI-induced inflammation and apoptosis via NF-kappaB and caspase-3 regulation in the male rat brain.Template:36959464
36092162 PDF 2022. Neuroprotective Effect and Possible Mechanisms of Ginsenoside-Rd for Cerebral Ischemia/Reperfusion Damage in Experimental Animal: A Meta-Analysis and Systematic Review.Template:36092162
34961206 PDF 2021. Astaxantin and Isoflavones Inhibit Benign Prostatic Hyperplasia in Rats by Reducing Oxidative Stress and Normalizing Ca/Mg Balance.Template:34961206
32878232 PDF 2020. Headaches and Magnesium: Mechanisms, Bioavailability, Therapeutic Efficacy and Potential Advantage of Magnesium Pidolate.Template:32878232
28684697 PDF 2017. Transient Receptor Potential (TRP) Channels in Drug Discovery: Old Concepts & New Thoughts.Template:28684697
22438954 PDF 2012. Carvacrol, a food-additive, provides neuroprotection on focal cerebral ischemia/reperfusion injury in mice.Template:22438954
37908255 PDF 2023. Improvement in Serum Magnesium Levels With Sodium-Glucose Cotransporter 2 Inhibitors.Template:37908255
35720215 PDF 2022. Supplementation of Carvacrol Attenuates Hippocampal Tumor Necrosis Factor-Alpha Level, Oxidative Stress, and Learning and Memory Dysfunction in Lipopolysaccharide-Exposed Rats.Template:35720215
34959740 PDF 2021. Dietary Magnesium Alleviates Experimental Murine Colitis through Modulation of Gut Microbiota.Template:34959740
33435187 PDF 2021. Effectively Prescribing Oral Magnesium Therapy for Hypertension: A Categorized Systematic Review of 49 Clinical Trials.Template:33435187
32971775 PDF 2020. Effect of Dietary Magnesium Content on Intestinal Microbiota of Rats.Template:32971775
31768494 PDF 2019. Mineral and Electrolyte Disorders With SGLT2i Therapy.Template:31768494
30093524 PDF 2018. Carboxamido steroids inhibit the opening properties of transient receptor potential ion channels by lipid raft modulation.Template:30093524
27448942 PDF 2016. Effects of Potassium Magnesium Citrate Supplementation on 24-Hour Ambulatory Blood Pressure and Oxidative Stress Marker in Prehypertensive and Hypertensive Subjects.Template:27448942
24936262 PDF 2014. Canagliflozin-current status in the treatment of type 2 diabetes mellitus with focus on clinical trial data.Template:24936262
24575172 PDF 2014. The role of nutrition and nutraceutical supplements in the treatment of hypertension.Template:24575172
23526071 PDF 2013. Additional antihypertensive effect of magnesium supplementation with an angiotensin II receptor blocker in hypomagnesemic rats.Template:23526071
18199759 PDF 2008. Transient receptor potential channels in sensory neurons are targets of the antimycotic agent clotrimazole.Template:18199759
30338939 PDF 2018. Prostaglandin E2 increases migration and proliferation of human glioblastoma cells by activating transient receptor potential melastatin 7 channels.Template:30338939
38188875 PDF 2023. Changes in the urinary proteome of rats after short-term intake of magnesium L-threonate(MgT).Template:38188875
34504876 PDF 2021. beta-Hydroxybutyric Inhibits Vascular Calcification via Autophagy Enhancement in Models Induced by High Phosphate.Template:34504876
26411768 PDF 2015. Psychiatric Disorders and TRP Channels: Focus on Psychotropic Drugs.Template:26411768
33369187 PDF 2021. Role of gut microbiota-derived metabolites on vascular calcification in CKD.Template:33369187
34684514 PDF 2021. The Impact of Multispecies Probiotics on Calcium and Magnesium Status in Healthy Male Rats.Template:34684514
34444763 PDF 2021. The Emerging Role of Nutraceuticals in Cardiovascular Calcification: Evidence from Preclinical and Clinical Studies.Template:34444763
36329098 PDF 2022. Butyrate reduces cellular magnesium absorption independently of metabolic regulation in Caco-2 human colon cells.Template:36329098
16895586 PDF 2006. Unconventional neuroprotection against Ca2+ -dependent insults by metalloporphyrin catalytic antioxidants.Template:16895586
37774552 PDF 2023. Calcium carbonate-actuated ion homeostasis perturbator for oxidative damage-augmented Ca(2+)/Mg(2+) interference therapy.Template:37774552
30541094 PDF 2018. Personalized magnesium intervention to improve vitamin D metabolism: applying a systems approach for precision nutrition in large randomized trials of diverse populations.Template:30541094