Fibrosis (TRPM7)

23934071 PDF 2013. Inhibition of TRPM7 channels prevents proliferation and differentiation of human lung fibroblasts.Template:23934071
18268139 PDF 2008. Downregulation of renal TRPM7 and increased inflammation and fibrosis in aldosterone-infused mice: effects of magnesium.Template:18268139
29500887 PDF 2018. TGFbeta-induced epithelial-to-mesenchymal transition in prostate cancer cells is mediated via TRPM7 expression.Template:29500887
25204892 PDF 2015. Novel insights into TRPM7 function in fibrotic diseases: a potential therapeutic target.Template:25204892
25150141 PDF 2014. TGF-beta1-elevated TRPM7 channel regulates collagen expression in hepatic stellate cells via TGF-beta1/Smad pathway.Template:25150141
24680379 PDF 2014. TRPM7 is involved in angiotensin II induced cardiac fibrosis development by mediating calcium and magnesium influx.Template:24680379
37072467 PDF 2023. CBGA ameliorates inflammation and fibrosis in nephropathy.Template:37072467
36384264 PDF 2022. TRPM7 Elicits Proliferation and Differentiation of Human Lens Epithelial Cells through the TGF-beta/Smad Pathways.Template:36384264
35883700 PDF 2022. TRPM7 Modulates Human Pancreatic Stellate Cell Activation.Template:35883700
35864199 PDF 2022. TRPM7 restrains plasmin activity and promotes transforming growth factor-beta1 signaling in primary human lung fibroblasts.Template:35864199
33922466 PDF 2021. Channelling the Force to Reprogram the Matrix: Mechanosensitive Ion Channels in Cardiac Fibroblasts.Template:33922466
33456540 PDF 2021. Role of TRPM7 in cardiac fibrosis: A potential therapeutic target (Review).Template:33456540
33284571 PDF 2020. MiR-149 attenuates the proliferation and migration of TGF-beta1-induced airway smooth muscle cells by targeting TRPM7 and affecting downstream MAPK signal pathway.Template:33284571
35850880 PDF 2023. Overexpression of TRPM7 promotes the therapeutic effect of curcumin in wound healing through the STAT3/SMAD3 signaling pathway in human fibroblasts.Template:35850880
33647257 PDF 2021. Carvacrol alleviates liver fibrosis by inhibiting TRPM7 and modulating the MAPK signaling pathway.Template:33647257
33494094 PDF 2021. Transient Receptor Potential Melastatin 7 Promotes Vascular Adventitial Fibroblasts Phenotypic Transformation and Inflammatory Reaction Induced by Mechanical Stretching Stress via p38 MAPK/JNK Pathway.Template:33494094
33143990 PDF 2021. Panax Notoginseng Saponins suppresses TRPM7 via the PI3K/AKT pathway to inhibit hypertrophic scar formation in vitro.Template:33143990
31739105 PDF 2020. Astragaloside IV inhibits cardiac fibrosis via miR-135a-TRPM7-TGF-beta/Smads pathway.Template:31739105
31640089 PDF 2019. TRPM7 deficiency suppresses cell proliferation, migration, and invasion in human colorectal cancer via regulation of epithelial-mesenchymal transition.Template:31640089
30445149 PDF 2019. TRP channels in cardiac and intestinal fibrosis.Template:30445149
30290314 PDF 2018. TGF-beta1-Induced Airway Smooth Muscle Cell Proliferation Involves TRPM7-Dependent Calcium Influx via TGFbetaR/SMAD3.Template:30290314
29775892 PDF 2018. MicroRNA-135a inhibits cardiac fibrosis induced by isoproterenol via TRPM7 channel.Template:29775892
29079194 PDF 2017. Role of ROS-TRPM7-ERK1/2 axis in high concentration glucose-mediated proliferation and phenotype switching of rat aortic vascular smooth muscle cells.Template:29079194
28573641 PDF 2017. Downregulation of TRPM7 suppressed migration and invasion by regulating epithelial-mesenchymal transition in prostate cancer cells.Template:28573641
28393175 PDF 2017. TRPM7 channels mediate the functional changes in cardiac fibroblasts induced by angiotensin II.Template:28393175
32706027 PDF 2020. Epidermal growth factor signaling through transient receptor potential melastatin 7 cation channel regulates vascular smooth muscle cell function.Template:32706027
32047249 PDF 2020. TRPM7 contributes to progressive nephropathy.Template:32047249
30819230 PDF 2019. TRPM7 promotes the epithelial-mesenchymal transition in ovarian cancer through the calcium-related PI3K / AKT oncogenic signaling.Template:30819230
29684587 PDF 2018. TRPM7 controls mesenchymal features of breast cancer cells by tensional regulation of SOX4.Template:29684587
29511803 PDF 2018. TRPM7 regulates angiotensin II-induced sinoatrial node fibrosis in sick sinus syndrome rats by mediating Smad signaling.Template:29511803
26164719 PDF 2015. Inhibition of TRPM7 Attenuates Rat Aortic Smooth Muscle Cell Proliferation Induced by Angiotensin II: Role of Genistein.Template:26164719
25863514 PDF 2015. Effects of laser irradiation at different wavelengths (660, 810, 980, and 1064 nm) on transient receptor potential melastatin channels in an animal model of wound healing.Template:25863514
27108806 PDF 2016. Upregulation of TRPM7 augments cell proliferation and interleukin-8 release in airway smooth muscle cells of rats exposed to cigarette smoke.Template:27108806
26900082 PDF 2016. TRPM7 channel regulates ox-LDL-induced proliferation and migration of vascular smooth muscle cells via MEK-ERK pathways.Template:26900082
24220678 PDF 2014. Blockage of TRPM7 channel induces hepatic stellate cell death through endoplasmic reticulum stress-mediated apoptosis.Template:24220678
23958495 PDF 2013. TRPM7 channel regulates PDGF-BB-induced proliferation of hepatic stellate cells via PI3K and ERK pathways.Template:23958495
24871786 PDF 2014. Transient receptor potential melastatin 7 (TRPM7) contributes to H2O2-induced cardiac fibrosis via mediating Ca(2+) influx and extracellular signal-regulated kinase 1/2 (ERK1/2) activation in cardiac fibroblasts.Template:24871786
24710004 PDF 2014. Endotoxin induces fibrosis in vascular endothelial cells through a mechanism dependent on transient receptor protein melastatin 7 activity.Template:24710004
24586847 PDF 2014. Magnesium inhibits Wnt/beta-catenin activity and reverses the osteogenic transformation of vascular smooth muscle cells.Template:24586847
23686305 PDF 2014. Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent.Template:23686305
23511028 PDF 2013. A TRP to cardiac fibroblast differentiation.Template:23511028
23432060 PDF 2013. Transient receptor potential (TRP) channels and cardiac fibrosis.Template:23432060
20075334 PDF 2010. TRPM7-mediated Ca2+ signals confer fibrogenesis in human atrial fibrillation.Template:20075334
36747205 PDF 2023. Empagliflozin suppressed cardiac fibrogenesis through sodium-hydrogen exchanger inhibition and modulation of the calcium homeostasis.Template:36747205
34331987 PDF 2021. Fibrosis of the diabetic heart: Clinical significance, molecular mechanisms, and therapeutic opportunities.Template:34331987
28506744 PDF 2017. Hepatic stellate cells as key target in liver fibrosis.Template:28506744
37138582 PDF 2023. Integrating Network Pharmacology and Experimental Validation to Explore the Pharmacological Mechanism of Astragaloside IV in Treating Bleomycin-Induced Pulmonary Fibrosis.Template:37138582
36408254 PDF 2022. Astragalus and its formulas as a therapeutic option for fibrotic diseases: Pharmacology and mechanisms.Template:36408254
36160396 PDF 2022. Astragalus Mongholicus: A review of its anti-fibrosis properties.Template:36160396
35656031 PDF 2022. Astragaloside IV Ameliorates Isoprenaline-Induced Cardiac Fibrosis in Mice via Modulating Gut Microbiota and Fecal Metabolites.Template:35656031
34811833 PDF 2022. Sorafenib attenuates liver fibrosis by triggering hepatic stellate cell ferroptosis via HIF-1alpha/SLC7A11 pathway.Template:34811833
34594406 PDF 2021. Se alleviates homocysteine-induced fibrosis in cardiac fibroblasts via downregulation of lncRNA MEG3.Template:34594406
36277193 PDF 2022. Ion channels as a therapeutic target for renal fibrosis.Template:36277193
33082445 PDF 2020. Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models.Template:33082445
37705977 PDF 2023. Multimodal roles of transient receptor potential channel activation in inducing pathological tissue scarification.Template:37705977
31250885 PDF 2020. Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis.Template:31250885
22406504 PDF 2012. Inhibition of transient receptor potential melastain 7 channel increases HSCs apoptosis induced by TRAIL.Template:22406504
35837047 PDF 2022. MicroRNA-146a attenuates isoproterenol-induced cardiac fibrosis by inhibiting FGF2.Template:35837047
35047019 PDF 2021. Single-Cell and Bulk Transcriptome Data Integration Reveals Dysfunctional Cell Types and Aberrantly Expressed Genes in Hypertrophic Scar.Template:35047019
33569393 PDF 2020. Pivotal Role of TGF-beta/Smad Signaling in Cardiac Fibrosis: Non-coding RNAs as Effectual Players.Template:33569393
32994970 PDF 2020. Malvidin induces hepatic stellate cell apoptosis via the endoplasmic reticulum stress pathway and mitochondrial pathway.Template:32994970
32341639 PDF 2020. Isoliquiritigenin Attenuates UUO-Induced Renal Inflammation and Fibrosis by Inhibiting Mincle/Syk/NF-Kappa B Signaling Pathway.Template:32341639
32104267 PDF 2020. miR-26b inhibits isoproterenol-induced cardiac fibrosis via the Keap1/Nrf2 signaling pathway.Template:32104267
31555353 PDF 2019. Plantamajoside exerts antifibrosis effects in the liver by inhibiting hepatic stellate cell activation.Template:31555353
31007736 PDF 2019. let-7a suppresses liver fibrosis via TGFbeta/SMAD signaling transduction pathway.Template:31007736
29057165 PDF 2017. Mechanisms of Fibroblast Activation in the Remodeling Myocardium.Template:29057165
28565783 PDF 2017. Traditional Chinese medicine baoxin decoction improves cardiac fibrosis of rats with dilated cardiomyopathy.Template:28565783
27332862 PDF 2016. New Developments on the Treatment of Liver Fibrosis.Template:27332862
23782569 PDF 2013. Cellular re- and de-programming by microenvironmental memory: why short TGF-beta1 pulses can have long effects.Template:23782569
23448358 PDF 2013. Function and fate of myofibroblasts after myocardial infarction.Template:23448358
14976548 PDF 2004. Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition.Template:14976548
37771726 PDF 2023. Drugs for treating myocardial fibrosis.Template:37771726
36969589 PDF 2023. Progress on role of ion channels of cardiac fibroblasts in fibrosis.Template:36969589
36843918 PDF 2023. Mechanism of action of non-coding RNAs and traditional Chinese medicine in myocardial fibrosis: Focus on the TGF-beta/Smad signaling pathway.Template:36843918
36299876 PDF 2022. Traditional Chinese medicine for hypertrophic scars-A review of the therapeutic methods and potential effects.Template:36299876
36277180 PDF 2022. Emerging role of transient receptor potential (TRP) ion channels in cardiac fibroblast pathophysiology.Template:36277180
35754495 PDF 2022. Research Progress of Traditional Chinese Medicine in Treatment of Myocardial fibrosis.Template:35754495
35615675 PDF 2022. Mechanical Stretch Triggers Epithelial-Mesenchymal Transition in Keratinocytes Through Piezo1 Channel.Template:35615675
35359592 PDF 2022. Focusing on Mechanoregulation Axis in Fibrosis: Sensing, Transduction and Effecting.Template:35359592
34483934 PDF 2021. Huangqi Shengmai Yin Ameliorates Myocardial Fibrosis by Activating Sirtuin3 and Inhibiting TGF-beta/Smad Pathway.Template:34483934
34055617 PDF 2021. Calcium Channel Protein ORAI1 Mediates TGF-beta Induced Epithelial-to-Mesenchymal Transition in Colorectal Cancer Cells.Template:34055617
33937049 PDF 2021. Resveratrol and Its Analogs: Potent Agents to Reverse Epithelial-to-Mesenchymal Transition in Tumors.Template:33937049
31849690 PDF 2019. PM(2.5), Fine Particulate Matter: A Novel Player in the Epithelial-Mesenchymal Transition?Template:31849690
30250825 PDF 2018. Transforming Growth Factor-beta-Induced Cell Plasticity in Liver Fibrosis and Hepatocarcinogenesis.Template:30250825
36950111 PDF 2023. Matrix stiffness induces epithelial-to-mesenchymal transition via Piezo1-regulated calcium flux in prostate cancer cells.Template:36950111
35897650 PDF 2022. Piezo1 Channel as a Potential Target for Hindering Cardiac Fibrotic Remodeling.Template:35897650
34984022 PDF 2021. Identification of ceRNA (lncRNA-miRNA-mRNA) Regulatory Network in Myocardial Fibrosis After Acute Myocardial Infarction.Template:34984022
34927020 PDF 2021. Liver sphingomyelin synthase 1 deficiency causes steatosis, steatohepatitis, fibrosis, and tumorigenesis: An effect of glucosylceramide accumulation.Template:34927020

34360952 PDF 2021. Transient Receptor Potential Channels in the Epithelial-to-Mesenchymal Transition.'

32705273 PDF 2020. Inhibition of miRNA‑135a‑5p ameliorates TGF‑beta1‑induced human renal fibrosis by targeting SIRT1 in diabetic nephropathy.Template:32705273
29115395 PDF 2018. Transforming growth factor beta1 promotes migration and invasion in HepG2 cells: Epithelial‑to‑mesenchymal transition via JAK/STAT3 signaling.Template:29115395
26909046 PDF 2016. Promising Therapy Candidates for Liver Fibrosis.Template:26909046
35671705 PDF 2023. Mannan-Binding Lectin Reduces Epithelial-Mesenchymal Transition in Pulmonary Fibrosis via Inactivating the Store-Operated Calcium Entry Machinery.Template:35671705
33028359 PDF 2020. Calreticulin promotes EMT in pancreatic cancer via mediating Ca(2+) dependent acute and chronic endoplasmic reticulum stress.Template:33028359
32047557 PDF 2020. Molecular Mechanism of Pancreatic Stellate Cells Activation in Chronic Pancreatitis and Pancreatic Cancer.Template:32047557
31547577 PDF 2019. Ca(2+) Signaling in Cardiac Fibroblasts and Fibrosis-Associated Heart Diseases.Template:31547577
30577808 PDF 2018. SIRT6 drives epithelial-to-mesenchymal transition and metastasis in non-small cell lung cancer via snail-dependent transrepression of KLF4.Template:30577808
30563389 PDF 2019. K(Ca)3.1 Channels Promote Cardiac Fibrosis Through Mediating Inflammation and Differentiation of Monocytes Into Myofibroblasts in Angiotensin II -Treated Rats.Template:30563389
28922779 PDF 2018. Targeting the Myofibroblastic Cancer-Associated Fibroblast Phenotype Through Inhibition of NOX4.Template:28922779
28550085 PDF 2017. Knockdown of sodium-calcium exchanger 1 induces epithelial-to-mesenchymal transition in kidney epithelial cells.Template:28550085
28332284 PDF 2017. EZH2-mediated repression of Dkk1 promotes hepatic stellate cell activation and hepatic fibrosis.Template:28332284
27167848 PDF 2016. Molecular networks underlying myofibroblast fate and fibrosis.Template:27167848
24189039 PDF 2014. Myofibroblasts: trust your heart and let fate decide.Template:24189039
32895361 PDF 2020. Lower Metal Element Levels in Hypertrophic Scars: A Potential Mechanism of Aberrant Cicatrix Hyperplasia.Template:32895361
32416242 PDF 2020. Regulators of cardiac fibroblast cell state.Template:32416242
32358524 PDF 2020. Context specificity of the EMT transcriptional response.Template:32358524
29119737 PDF 2017. Endostatin inhibits fibrosis by modulating the PDGFR/ERK signal pathway: an in vitro study.Template:29119737
28099257 PDF 2017. Antifibrotic Effect of Saturated Fatty Acids via Endoplasmic Reticulum Stress Response in Rat Pancreatic Stellate Cells.Template:28099257
22370643 PDF 2013. MiR-1 and miR-200 inhibit EMT via Slug-dependent and tumorigenesis via Slug-independent mechanisms.Template:22370643
20501797 PDF 2010. Na,K-ATPase subunits as markers for epithelial-mesenchymal transition in cancer and fibrosis.Template:20501797
35836819 PDF 2022. Loss of MLKL ameliorates liver fibrosis by inhibiting hepatocyte necroptosis and hepatic stellate cell activation.Template:35836819
34158869 PDF 2021. Elevated IgE promotes cardiac fibrosis by suppressing miR-486a-5p.Template:34158869
33500351 PDF 2021. GRK5 is a regulator of fibroblast activation and cardiac fibrosis.Template:33500351
35117228 PDF 2020. MEST promotes bladder cancer cell proliferation, migration and invasion via STAT3/Twist-1-mediated EMT.Template:35117228
32632340 PDF 2020. Prostate Cancer Epithelial Mesenchymal Transition by TGF-beta1 exposure monitored with a Photonic Crystal Biosensor.Template:32632340
31719171 PDF 2019. Translocation of TRPV4-PI3Kgamma complexes to the plasma membrane drives myofibroblast transdifferentiation.Template:31719171
31476281 PDF 2019. siRNA- and miRNA-based therapeutics for liver fibrosis.Template:31476281
28507335 PDF 2017. BNIP3L promotes cardiac fibrosis in cardiac fibroblasts through [Ca(2+)](i)-TGF-beta-Smad2/3 pathway.Template:28507335
28546859 PDF 2016. STAT3 Inhibition Suppresses Hepatic Stellate Cell Fibrogenesis: HJC0123, a Potential Therapeutic Agent for Liver Fibrosis.Template:28546859
30254408 PDF 2018. Daikenchuto (Da-Jian-Zhong-Tang) ameliorates intestinal fibrosis by activating myofibroblast transient receptor potential ankyrin 1 channel.Template:30254408
26109801 PDF 2015. Protective effect of bicyclol against bile duct ligation-induced hepatic fibrosis in rats.Template:26109801
36970190 PDF 2023. S1PR1 serves as a viable drug target against pulmonary fibrosis by increasing the integrity of the endothelial barrier of the lung.Template:36970190
35884879 PDF 2022. Klotho Modulates Pro-Fibrotic Activities in Human Atrial Fibroblasts through Inhibition of Phospholipase C Signaling and Suppression of Store-Operated Calcium Entry.Template:35884879
35517894 PDF 2022. Curcumin Prevents Epithelial-to Mesenchymal Transition-Mediated Ovarian Cancer Progression through NRF2/ETBR/ET-1 Axis and Preserves Mitochondria Biogenesis in Kidney after Cisplatin Administration.Template:35517894
35148253 PDF 2022. ASK1 Regulates Bleomycin-induced Pulmonary Fibrosis.Template:35148253
33014530 PDF 2020. Roles of Biomarkers in Myocardial Fibrosis.Template:33014530
31486669 PDF 2020. The Role of KCNMB1 and BK Channels in Myofibroblast Differentiation and Pulmonary Fibrosis.Template:31486669
27398165 PDF 2016. Anticytoproliferative effect of Vitamin C on rat hepatic stellate cell.Template:27398165
26047667 PDF 2016. Experimental models of liver fibrosis.Template:26047667
35136027 PDF 2022. ECM1 modified HF-MSCs targeting HSC attenuate liver cirrhosis by inhibiting the TGF-beta/Smad signaling pathway.Template:35136027
34831281 PDF 2021. TRPV4 Mechanotransduction in Fibrosis.Template:34831281
34359993 PDF 2021. Fibrosis, the Bad Actor in Cardiorenal Syndromes: Mechanisms Involved.Template:34359993

32673537 PDF 2020. Myofibroblasts and Fibrosis: Mitochondrial and Metabolic Control of Cellular Differentiation.'

32329036 PDF 2020. Transient receptor potential channel TRPV4 mediates TGF-beta1-induced differentiation of human ventricular fibroblasts.Template:32329036
32085494 PDF 2020. Cellular Interplay as a Consequence of Inflammatory Signals Leading to Liver Fibrosis Development.Template:32085494
32065054 PDF 2020. T-Cell-Derived miRNA-214 Mediates Perivascular Fibrosis in Hypertension.Template:32065054
31758702 PDF 2020. Ca(2+) signalling in fibroblasts and the therapeutic potential of K(Ca)3.1 channel blockers in fibrotic diseases.Template:31758702
30796204 PDF 2019. circHIPK3 regulates lung fibroblast-to-myofibroblast transition by functioning as a competing endogenous RNA.Template:30796204
29552620 PDF 2018. Activation of Myofibroblast TRPA1 by Steroids and Pirfenidone Ameliorates Fibrosis in Experimental Crohn's Disease.Template:29552620
36674805 PDF 2023. Calcium-Signalling in Human Glaucoma Lamina Cribrosa Myofibroblasts.Template:36674805
24935972 PDF 2014. Endotoxin-induced endothelial fibrosis is dependent on expression of transforming growth factors beta1 and beta2.Template:24935972

23635013 PDF 2013. Lipopolysaccharide induces a fibrotic-like phenotype in endothelial cells.'

32730639 PDF 2021. Melatonin ameliorates PM(2.5) -induced cardiac perivascular fibrosis through regulating mitochondrial redox homeostasis.Template:32730639

30864875 PDF 2019. Endothelial to Mesenchymal Transition: Role in Physiology and in the Pathogenesis of Human Diseases.'

32606340 PDF 2020. Investigating the antifibrotic effect of the antiparasitic drug Praziquantel in in vitro and in vivo preclinical models.Template:32606340
37431884 PDF 2023. Oridonin suppresses gastric cancer SGC-7901 cell proliferation by targeting the TNF-alpha/androgen receptor/TGF-beta signalling pathway axis.Template:37431884