Template:32734187

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Revision as of 21:37, 31 January 2024 by Ossip Groth (talk | contribs) (Created page with "sim. of crystalglobin-associated nephropathy: monoclonal protein–related crystalline nephropathies, light chain proximal tubulopathy, crystalline light chain cast nephropathy, crystal-storing histiocytosis, cryocrystalglobulinemia. table of all Monoclonal Protein–Related Renal Lesions given. mech: crystallization in endoplasmic reticulum, lysosomes (re-uptake), the in capillary lumina as TMA-lookalikes or small-vessel vasculitis. lm: nospecific, subsensitive ihc, eo...")
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sim. of crystalglobin-associated nephropathy: monoclonal protein–related crystalline nephropathies, light chain proximal tubulopathy, crystalline light chain cast nephropathy, crystal-storing histiocytosis, cryocrystalglobulinemia. table of all Monoclonal Protein–Related Renal Lesions given.

mech: crystallization in endoplasmic reticulum, lysosomes (re-uptake), the in capillary lumina as TMA-lookalikes or small-vessel vasculitis. lm: nospecific, subsensitive ihc, eosinophilic material, pronase-digest stains Ig.

lab: myeloma workup, free light chains, marrow biopsy, albumin-autoantibodies, cryoglobulins.

treat: independent of myeloma activity chemo, cases bone marrow transplant. heroic plasmapherisis.

case: rpgn as tma-like lesion, corneal(eye) deposits (img shown)

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