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(Created page with "sim. of crystalglobin-associated nephropathy: monoclonal protein–related crystalline nephropathies, light chain proximal tubulopathy, crystalline light chain cast nephropathy, crystal-storing histiocytosis, cryocrystalglobulinemia. table of all Monoclonal Protein–Related Renal Lesions given. mech: crystallization in endoplasmic reticulum, lysosomes (re-uptake), the in capillary lumina as TMA-lookalikes or small-vessel vasculitis. lm: nospecific, subsensitive ihc, eo...")
 
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sim. of crystalglobin-associated nephropathy: monoclonal protein–related crystalline nephropathies, light chain proximal tubulopathy, crystalline light chain cast nephropathy, crystal-storing histiocytosis, cryocrystalglobulinemia.
*sim. of crystalglobin-associated nephropathy: monoclonal protein–related crystalline nephropathies, light chain proximal tubulopathy, crystalline light chain cast nephropathy, crystal-storing histiocytosis, cryocrystalglobulinemia.
table of all Monoclonal Protein–Related Renal Lesions given.
table of all Monoclonal Protein–Related Renal Lesions given.
 
*mech: crystallization in endoplasmic reticulum, lysosomes (re-uptake), the in capillary lumina as TMA-lookalikes or small-vessel vasculitis. lm: nospecific, subsensitive ihc, eosinophilic material, pronase-digest stains Ig.
mech: crystallization in endoplasmic reticulum, lysosomes (re-uptake), the in capillary lumina as TMA-lookalikes or small-vessel vasculitis. lm: nospecific, subsensitive ihc, eosinophilic material, pronase-digest stains Ig.
*lab: myeloma workup, free light chains, marrow biopsy, albumin-autoantibodies, cryoglobulins.
 
*treat: independent of myeloma activity chemo, cases bone marrow transplant. heroic plasmapherisis.
lab: myeloma workup, free light chains, marrow biopsy, albumin-autoantibodies, cryoglobulins.
*case: rpgn as tma-like lesion, corneal(eye) deposits (img shown)
 
treat: independent of myeloma activity chemo, cases bone marrow transplant. heroic plasmapherisis.
 
case: rpgn as tma-like lesion, corneal(eye) deposits (img shown)

Latest revision as of 22:36, 31 January 2024

  • sim. of crystalglobin-associated nephropathy: monoclonal protein–related crystalline nephropathies, light chain proximal tubulopathy, crystalline light chain cast nephropathy, crystal-storing histiocytosis, cryocrystalglobulinemia.

table of all Monoclonal Protein–Related Renal Lesions given.

  • mech: crystallization in endoplasmic reticulum, lysosomes (re-uptake), the in capillary lumina as TMA-lookalikes or small-vessel vasculitis. lm: nospecific, subsensitive ihc, eosinophilic material, pronase-digest stains Ig.
  • lab: myeloma workup, free light chains, marrow biopsy, albumin-autoantibodies, cryoglobulins.
  • treat: independent of myeloma activity chemo, cases bone marrow transplant. heroic plasmapherisis.
  • case: rpgn as tma-like lesion, corneal(eye) deposits (img shown)