Diabetes (TRPM7)

36717580 PDF 2023. Adipose-specific deletion of the cation channel TRPM7 inhibits TAK1 kinase-dependent inflammation and obesity in male mice.Template:36717580
36574297 PDF 2023. TRPM7 kinase is required for insulin production and compensatory islet responses during obesity.Template:36574297
34865947 PDF 2022. Associations between gene expression of magnesium transporters and glucose metabolism in pregnancy.Template:34865947
34345920 PDF 2021. TRPM7 is a crucial regulator of pancreatic endocrine development and high-fat-diet-induced beta-cell proliferation.Template:34345920
34072724 PDF 2021. The Combined Influence of Magnesium and Insulin on Central Metabolic Functions and Expression of Genes Involved in Magnesium Homeostasis of Cultured Bovine Adipocytes.Template:34072724
33891828 PDF 2021. Leptin Induces Epigenetic Regulation of Transient Receptor Potential Melastatin 7 in Rat Adrenal Pheochromocytoma Cells.Template:33891828
37837806 PDF 2023. Improvement of actin dynamics and cognitive impairment in diabetes through troxerutin-mediated downregulation of TRPM7/CaN/cofilin.Template:37837806
31697634 PDF 2019. Leptin Activates Trpm7 Channels in the Carotid Body As a Mechanism of Obesity-Related Hypertension.Template:31697634
27574117 PDF 2016. Intersection of calorie restriction and magnesium in the suppression of genome-destabilizing RNA-DNA hybrids.Template:27574117
24057349 PDF 2014. Functional TRPV and TRPM channels in human preadipocytes.Template:24057349
23765921 PDF 2014. TRPM7 channels regulate proliferation and adipogenesis in 3T3-L1 preadipocytes.Template:23765921
20875900 PDF 2010. Gene variation of the transient receptor potential cation channel, subfamily M, members 6 (TRPM6) and 7 (TRPM7), and type 2 diabetes mellitus: a case-control study.Template:20875900
19098369 PDF 2008. The role of transient receptor potential channels in metabolic syndrome.Template:19098369
30742025 PDF 2019. Diabetes-induced hypomagnesemia is not modulated by metformin treatment in mice.Template:30742025
34331987 PDF 2021. Fibrosis of the diabetic heart: Clinical significance, molecular mechanisms, and therapeutic opportunities.Template:34331987
32393384 PDF 2020. Effect of long-term treatment of Carvacrol on glucose metabolism in Streptozotocin-induced diabetic mice.Template:32393384
31604444 PDF 2019. Hypomagnesemia is associated with new-onset diabetes mellitus following heart transplantation.Template:31604444
38186879 PDF 2024. Mechanisms and treatment of obesity-related hypertension-Part 1: Mechanisms.Template:38186879

36741996 PDF 2022. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.'

36346820 PDF 2023. Hypomagnesemia and Cardiovascular Risk in Type 2 Diabetes.Template:36346820
35445032 PDF 2022. Dysregulated Erythroid Mg(2+) Efflux in Type 2 Diabetes.Template:35445032
34277971 PDF 2021. Canagliflozin, serum magnesium and cardiovascular outcomes-Analysis from the CANVAS Program.Template:34277971
33866775 PDF 2021. Lobeglitazone: A Novel Thiazolidinedione for the Management of Type 2 Diabetes Mellitus.Template:33866775
33747462 PDF 2021. Association of dietary calcium, magnesium, and vitamin D with type 2 diabetes among US adults: National health and nutrition examination survey 2007-2014-A cross-sectional study.Template:33747462
31196609 PDF 2019. Ion channels and transporters in diabetic kidney disease.Template:31196609
28224192 PDF 2017. Serum magnesium and the risk of prediabetes: a population-based cohort study.Template:28224192
28197834 PDF 2017. Effects of Canagliflozin on Serum Magnesium in Patients With Type 2 Diabetes Mellitus: A Post Hoc Analysis of Randomized Controlled Trials.Template:28197834
33716794 PDF 2021. Vascular Dysfunction in Diabetes and Obesity: Focus on TRP Channels.Template:33716794
31572181 PDF 2019. Carvacrol Attenuates Diabetic Cardiomyopathy by Modulating the PI3K/AKT/GLUT4 Pathway in Diabetic Mice.Template:31572181
30889804 PDF 2019. Effects of Magnesium Deficiency on Mechanisms of Insulin Resistance in Type 2 Diabetes: Focusing on the Processes of Insulin Secretion and Signaling.Template:30889804
28508457 PDF 2017. Effects of canagliflozin on cardiovascular risk factors in patients with type 2 diabetes mellitus.Template:28508457
37441489 PDF 2023. Reduced Levels of the Antiaging Hormone Klotho are Associated With Increased Aortic Stiffness in Diabetic Kidney Disease.Template:37441489
36837924 PDF 2023. Hypomagnesemia as a Risk Factor and Accelerator for Vascular Aging in Diabetes Mellitus and Chronic Kidney Disease.Template:36837924
36185705 PDF 2022. Sodium-Glucose Cotransporter 2 Inhibitors and Management of Refractory Hypomagnesemia Without Overt Urinary Magnesium Wasting: A Report of 2 Cases.Template:36185705
35565682 PDF 2022. The Role of Magnesium in the Pathogenesis of Metabolic Disorders.Template:35565682
35277073 PDF 2022. Magnesium in Type 2 Diabetes Mellitus, Obesity, and Metabolic Syndrome.Template:35277073
34836340 PDF 2021. Effect of Dapagliflozin and Magnesium Supplementation on Renal Magnesium Handling and Magnesium Homeostasis in Metabolic Syndrome.Template:34836340
31446746 PDF 2019. Transient Receptor Potential Channels and Metabolism.Template:31446746
25733456 PDF 2015. Genetic variations in magnesium-related ion channels may affect diabetes risk among African American and Hispanic American women.Template:25733456
23343670 PDF 2013. Higher magnesium intake is associated with lower fasting glucose and insulin, with no evidence of interaction with select genetic loci, in a meta-analysis of 15 CHARGE Consortium Studies.Template:23343670
33499378 PDF 2021. Magnesium in Obesity, Metabolic Syndrome, and Type 2 Diabetes.Template:33499378
33447354 PDF 2020. Hypomagnesemia in persons with type 1 diabetes: associations with clinical parameters and oxidative stress.Template:33447354
33396318 PDF 2020. Low Dietary Magnesium and Overweight/Obesity in a Mediterranean Population: A Detrimental Synergy for the Development of Hypertension. The SUN Project.Template:33396318
30742025 PDF 2019. Diabetes-induced hypomagnesemia is not modulated by metformin treatment in mice.Template:30742025
24322525 PDF 2013. Dietary magnesium and genetic interactions in diabetes and related risk factors: a brief overview of current knowledge.Template:24322525
37908255 PDF 2023. Improvement in Serum Magnesium Levels With Sodium-Glucose Cotransporter 2 Inhibitors.Template:37908255
36684386 PDF 2023. Association of vitamin D and magnesium with insulin sensitivity and their influence on glycemic control.Template:36684386
31768494 PDF 2019. Mineral and Electrolyte Disorders With SGLT2i Therapy.Template:31768494

30717286 PDF 2019. Lower Plasma Magnesium, Measured by Nuclear Magnetic Resonance Spectroscopy, is Associated with Increased Risk of Developing Type 2 Diabetes Mellitus in Women: Results from a Dutch Prospective Cohort Study.'

26265998 PDF 2015. Epigenetic profiles of pre-diabetes transitioning to type 2 diabetes and nephropathy.Template:26265998
24936262 PDF 2014. Canagliflozin-current status in the treatment of type 2 diabetes mellitus with focus on clinical trial data.Template:24936262
33716794 PDF 2021. Vascular Dysfunction in Diabetes and Obesity: Focus on TRP Channels.Template:33716794

30717286 PDF 2019. Lower Plasma Magnesium, Measured by Nuclear Magnetic Resonance Spectroscopy, is Associated with Increased Risk of Developing Type 2 Diabetes Mellitus in Women: Results from a Dutch Prospective Cohort Study.'

37121975 PDF 2023. Candesartan, an angiotensin-II receptor blocker, ameliorates insulin resistance and hepatosteatosis by reducing intracellular calcium overload and lipid accumulation.Template:37121975
36147580 PDF 2022. Non-coding RNAs in diabetes mellitus and diabetic cardiovascular disease.Template:36147580
35073578 PDF 2022. Sulfated Progesterone Metabolites That Enhance Insulin Secretion via TRPM3 Are Reduced in Serum From Women With Gestational Diabetes Mellitus.Template:35073578
34814650 PDF 2021. Ion channels alterations in the forebrain of high-fat diet fed rats.Template:34814650
34554282 PDF 2022. IAPP-induced beta cell stress recapitulates the islet transcriptome in type 2 diabetes.Template:34554282
34402473 PDF 2021. Glucagon is associated with NAFLD inflammatory progression in type 2 diabetes, not with NAFLD fibrotic progression.Template:34402473
35733856 PDF 2022. Circ_0004951 Promotes Pyroptosis of Renal Tubular Cells via the NLRP3 Inflammasome in Diabetic Kidney Disease.Template:35733856
33679451 PDF 2021. Cardiovascular and Metabolic Crosstalk in the Brain: Leptin and Resistin.Template:33679451
30524286 PDF 2018. Gastrodin Ameliorates Cognitive Dysfunction in Diabetes Rat Model via the Suppression of Endoplasmic Reticulum Stress and NLRP3 Inflammasome Activation.Template:30524286
28217522 PDF 2017. A review of clinical efficacy and safety of canagliflozin 300 mg in the management of patients with type 2 diabetes mellitus.Template:28217522
35967128 PDF 2022. Expression of Transient Receptor Potential Channel Genes and Their Isoforms in Alpha-Cells and Beta-Cells of Human Islets of Langerhans.Template:35967128
33729996 PDF 2021. Neuritin inhibits astrogliosis to ameliorate diabetic cognitive dysfunction.Template:33729996
33374507 PDF 2020. The Importance of Non-Coding RNAs in Neurodegenerative Processes of Diabetes-Related Molecular Pathways.Template:33374507
32439805 PDF 2020. The magnesium transporter NIPAL1 is a pancreatic islet-expressed protein that conditionally impacts insulin secretion.Template:32439805
31974165 PDF 2020. Metformin lowers glucose 6-phosphate in hepatocytes by activation of glycolysis downstream of glucose phosphorylation.Template:31974165
28811850 PDF 2017. Effect of Sodium Glucose Cotransporter 2 Inhibitors With Low SGLT2/SGLT1 Selectivity on Circulating Glucagon-Like Peptide 1 Levels in Type 2 Diabetes Mellitus.Template:28811850
28630088 PDF 2017. The islet-resident macrophage is in an inflammatory state and senses microbial products in blood.Template:28630088
37790634 PDF 2023. Loss of Farnesoid X receptor (FXR) accelerates dysregulated glucose and renal injury in db/db mice.Template:37790634
36571340 PDF 2023. Epigenetic modifications and metabolic memory in diabetic retinopathy: beyond the surface.Template:36571340
34836963 PDF 2021. CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease.Template:34836963
28436964 PDF 2017. SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis.Template:28436964
35778900 PDF 2022. Leptin-mediated neural targets in obesity hypoventilation syndrome.Template:35778900
33854178 PDF 2021. SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways.

33544938 PDF 2021. Metabolic sensor O-GlcNAcylation regulates megakaryopoiesis and thrombopoiesis through c-Myc stabilization and integrin perturbation.'

37988198 PDF 2023. Investigating EGF and PAG1 as necroptosis-related biomarkers for diabetic nephropathy: an in silico and in vitro validation study.Template:37988198
34927008 PDF 2021. Metformin for Cardiovascular Protection, Inflammatory Bowel Disease, Osteoporosis, Periodontitis, Polycystic Ovarian Syndrome, Neurodegeneration, Cancer, Inflammation and Senescence: What Is Next?Template:34927008
33402547 PDF 2021. The near-infrared dye IR-61 restores erectile function in a streptozotocin-induced diabetes model via mitochondrial protection.Template:33402547
38118414 PDF 2023. Dapagliflozin protects against chronic heart failure in mice by inhibiting macrophage-mediated inflammation, independent of SGLT2.Template:38118414
21171985 PDF 2010. Increased plasma soluble endoglin levels as an indicator of cardiovascular alterations in hypertensive and diabetic patients.Template:21171985
33195411 PDF 2020. A Transcriptomic Analysis Reveals Novel Patterns of Gene Expression During 3T3-L1 Adipocyte Differentiation.Template:33195411
32168890 PDF 2020. Molecular Regulations and Functions of the Transient Receptor Potential Channels of the Islets of Langerhans and Insulinoma Cells.Template:32168890
32162606 PDF 2019. Reactive oxygen species are implicated in altering magnesium homeostasis in endothelial cells exposed to high glucose.Template:32162606
31650715 PDF 2019. Functional expression of TRPM7 as a Ca(2+) influx pathway in adipocytes.Template:31650715
31163064 PDF 2019. Low extracellular magnesium does not impair glucose-stimulated insulin secretion.Template:31163064
37282948 PDF 2023. [Lianmei Qiwu Decoction relieves diabetic cardiac autonomic neuropathy by regulating AMPK/TrkA/TRPM7 signaling pathway].Template:37282948
31180948 PDF 2019. Magnesium-responsive genes are downregulated in diabetic patients after a three-month exercise program on a bicycle ergometer.Template:31180948
27464700 PDF 2017. Expression of Transient Receptor Potential Channels in the Purified Human Pancreatic beta-Cells.Template:27464700
36421426 PDF 2022. Citronellal Attenuates Oxidative Stress-Induced Mitochondrial Damage through TRPM2/NHE1 Pathway and Effectively Inhibits Endothelial Dysfunction in Type 2 Diabetes Mellitus.Template:36421426
35656112 PDF 2022. DR1 Activation Inhibits the Proliferation of Vascular Smooth Muscle Cells through Increasing Endogenous H(2)S in Diabetes.Template:35656112
34944530 PDF 2021. Insulin-Responsive Transcription Factors.Template:34944530
34631209 PDF 2021. Targeting NLRP3 Inflammasome in the Treatment Of Diabetes and Diabetic Complications: Role of Natural Compounds from Herbal Medicine.Template:34631209
34452694 PDF 2021. The new kids on the block: Emerging obesogens.Template:34452694
34359828 PDF 2021. The Role of cAMP in Beta Cell Stimulus-Secretion and Intercellular Coupling.Template:34359828
34180254 PDF 2022. Contribution of Mitochondria to Insulin Secretion by Various Secretagogues.Template:34180254
33672062 PDF 2021. Lipotoxic Impairment of Mitochondrial Function in beta-Cells: A Review.Template:33672062
33572903 PDF 2021. The Pancreatic beta-Cell: The Perfect Redox System.Template:33572903
23651844 PDF 2013. Enhanced insulin clearance in mice lacking TRPM8 channels.Template:23651844
22275755 PDF 2012. TRPM2 Ca2+ channel regulates energy balance and glucose metabolism.Template:22275755
37731140 PDF 2023. Secondary diabetes mellitus in pheochromocytomas and paragangliomas.Template:37731140
36589805 PDF 2022. Mechanistic investigations of diabetic ocular surface diseases.Template:36589805
36467075 PDF 2022. Glucose-lowering effect of berberine on type 2 diabetes: A systematic review and meta-analysis.Template:36467075
36239048 PDF 2022. Phase 2 trial with imeglimin in patients with Type 2 diabetes indicates effects on insulin secretion and sensitivity.Template:36239048
36057030 PDF 2022. Pharmacokinetics of Oral Rebaudioside A in Patients with Type 2 Diabetes Mellitus and Its Effects on Glucose Homeostasis: A Placebo-Controlled Crossover Trial.Template:36057030
35872985 PDF 2022. The Extraglycemic Effect of SGLT-2is on Mineral and Bone Metabolism and Bone Fracture.Template:35872985
35387335 PDF 2022. Potential Therapeutic Targets of Rehmannia Formulations on Diabetic Nephropathy: A Comparative Network Pharmacology Analysis.Template:35387335
35069450 PDF 2021. Liraglutide Activates Type 2 Deiodinase and Enhances beta3-Adrenergic-Induced Thermogenesis in Mouse Adipose Tissue.Template:35069450
34636409 PDF 2021. Beta-Cell Ion Channels and Their Role in Regulating Insulin Secretion.Template:34636409
33150398 PDF 2021. Tissue-Specific Effects of Leptin on Glucose and Lipid Metabolism.Template:33150398
32848741 PDF 2020. Ionic Channels as Potential Therapeutic Targets for Erectile Dysfunction: A Review.Template:32848741
32280378 PDF 2020. Melatonin: new insights on its therapeutic properties in diabetic complications.Template:32280378
31231424 PDF 2019. Genetic and Epigenetic Studies in Diabetic Kidney Disease.Template:31231424
30364192 PDF 2018. Dissecting the Physiology and Pathophysiology of Glucagon-Like Peptide-1.Template:30364192
29201240 PDF 2017. Glucagon-like peptide-1 potentiates glucose-stimulated insulin secretion via the transient receptor potential melastatin 2 channel.Template:29201240
23734095 PDF 2013. Ion channels in the central regulation of energy and glucose homeostasis.Template:23734095
36453164 PDF 2023. Current understanding of imeglimin action on pancreatic beta-cells: Involvement of mitochondria and endoplasmic reticulum homeostasis.Template:36453164
34523242 PDF 2022. A novel mechanism of imeglimin-mediated insulin secretion via the cADPR-TRP channel pathway.Template:34523242
32129549 PDF 2020. Transient receptor potential vanilloid 4 channels as therapeutic targets in diabetes and diabetes-related complications.Template:32129549
31998809 PDF 2020. Role of Transient Receptor Potential Canonical Channel 6 (TRPC6) in Diabetic Kidney Disease by Regulating Podocyte Actin Cytoskeleton Rearrangement.Template:31998809
30125956 PDF 2019. Pulmonary vascular dysfunction in metabolic syndrome.Template:30125956
30613832 PDF 2017. Role of Transient Receptor Potential Channels Trpv1 and Trpm8 in Diabetic Peripheral Neuropathy.Template:30613832
36984867 PDF 2023. Genetic Markers of Insulin Resistance and Atherosclerosis in Type 2 Diabetes Mellitus Patients with Coronary Artery Disease.Template:36984867
36966947 PDF 2023. Neuronal loss of TRPM8 leads to obesity and glucose intolerance in male mice.Template:36966947
36677809 PDF 2023. GLP-1R Signaling and Functional Molecules in Incretin Therapy.Template:36677809
34777695 PDF 2021. The Mitochondrial-Associated Endoplasmic Reticulum Membrane and Its Role in Diabetic Nephropathy.Template:34777695
33606763 PDF 2021. Protective effects of dapagliflozin against oxidative stress-induced cell injury in human proximal tubular cells.Template:33606763
29088850 PDF 2017. Dietary menthol-induced TRPM8 activation enhances WAT "browning" and ameliorates diet-induced obesity.Template:29088850
25059284 PDF 2014. Oxidative stress increases pulmonary vascular permeability in diabetic rats through activation of transient receptor potential melastatin 2 channels.Template:25059284
34029747 PDF 2021. Cutaneous innervation in impaired diabetic wound healing.Template:34029747
32863218 PDF 2020. Metformin alleviates lead-induced mitochondrial fragmentation via AMPK/Nrf2 activation in SH-SY5Y cells.Template:32863218
29707621 PDF 2018. Improved Glucose Tolerance in a Kidney Transplant Recipient With Type 2 Diabetes Mellitus After Switching From Tacrolimus To Belatacept: A Case Report and Review of Potential Mechanisms.Template:29707621
27649495 PDF 2016. Renoprotective Effects of Atorvastatin in Diabetic Mice: Downregulation of RhoA and Upregulation of Akt/GSK3.Template:27649495