Vascular Calcification (TRPM7)

From Magnesium


23229924 PDF 2013. Magnesium prevents phosphate-induced calcification in human aortic vascular smooth muscle cells.Template:23229924
36984673 PDF 2023. The Interplay between TRPM7 and MagT1 in Maintaining Endothelial Magnesium Homeostasis.Template:36984673
32800835 PDF 2020. The role of TRPM7 in vascular calcification: Comparison between phosphate and uremic toxin.Template:32800835
28860220 PDF 2017. Interleukin-18 Enhances Vascular Calcification and Osteogenic Differentiation of Vascular Smooth Muscle Cells Through TRPM7 Activation.Template:28860220
32038296 PDF 2019. Endothelial Transient Receptor Potential Channels and Vascular Remodeling: Extracellular Ca(2 +) Entry for Angiogenesis, Arteriogenesis and Vasculogenesis.Template:32038296
31559137 PDF 2019. Magnesium Regulates Endothelial Barrier Functions through TRPM7, MagT1, and S1P1.Template:31559137

29391410 PDF 2018. Magnesium prevents vascular calcification in vitro by inhibition of hydroxyapatite crystal formation.'

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26268950 PDF 2015. Angiotensin II prevents calcification in vascular smooth muscle cells by enhancing magnesium influx.'

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28134400 PDF 2016. L'influenza del fosforo, del calcio e del magnesio sulla proteina Gla di matrice e sul processo di calcificazione vascolare: una review sistematica.Template:28134400
24026041 PDF 2014. The interaction of transient receptor potential melastatin 7 with macrophages promotes vascular adventitial remodeling in transverse aortic constriction rats.Template:24026041
22896586 PDF 2012. Upregulation of TRPM7 channels by angiotensin II triggers phenotypic switching of vascular smooth muscle cells of ascending aorta.Template:22896586
22183257 PDF 2012. Silencing TRPM7 mimics the effects of magnesium deficiency in human microvascular endothelial cells.Template:22183257
21290323 PDF 2011. TRPM channels in the vasculature.Template:21290323
19103997 PDF 2009. Dysregulation of vascular TRPM7 and annexin-1 is associated with endothelial dysfunction in inherited hypomagnesemia.Template:19103997
25472964 PDF 2015. TRPM7 regulates vascular endothelial cell adhesion and tube formation.Template:25472964
24710004 PDF 2014. Endotoxin induces fibrosis in vascular endothelial cells through a mechanism dependent on transient receptor protein melastatin 7 activity.Template:24710004
24586847 PDF 2014. Magnesium inhibits Wnt/beta-catenin activity and reverses the osteogenic transformation of vascular smooth muscle cells.Template:24586847
24223965 PDF 2013. Role of TRPM7 channels in hyperglycemia-mediated injury of vascular endothelial cells.Template:24223965
23533657 PDF 2013. Regulation and function of TRPM7 in human endothelial cells: TRPM7 as a potential novel regulator of endothelial function.Template:23533657
16857972 PDF 2006. Transient receptor potential channels in cardiovascular function and disease.Template:16857972
16842858 PDF 2006. Cation channels of the transient receptor potential superfamily: their role in physiological and pathophysiological processes of smooth muscle cells.Template:16842858
16456106 PDF 2006. Going with the flow: smooth muscle TRPM7 channels and the vascular response to blood flow.Template:16456106 str

16357306 PDF 2006. Functional TRPM7 channels accumulate at the plasma membrane in response to fluid flow.'

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22566504 PDF 2012. Pulsatile atheroprone shear stress affects the expression of transient receptor potential channels in human endothelial cells.Template:22566504
21199786 PDF 2010. Vascular biology of magnesium and its transporters in hypertension.Template:21199786
21150127 PDF 2011. Transient receptor potential melastatin 7 (TRPM7) cation channels, magnesium and the vascular system in hypertension.Template:21150127
20696983 PDF 2010. Vascular smooth muscle cell differentiation to an osteogenic phenotype involves TRPM7 modulation by magnesium.Template:20696983
20536737 PDF 2010. Vanilloid and melastatin transient receptor potential channels in vascular smooth muscle.Template:20536737
19454490 PDF 2009. Silencing TRPM7 promotes growth/proliferation and nitric oxide production of vascular endothelial cells via the ERK pathway.Template:19454490
18192217 PDF 2008. Transient receptor potential melastatin 6 and 7 channels, magnesium transport, and vascular biology: implications in hypertension.Template:18192217
18029156 PDF 2007. Magnesium transport in hypertension.Template:18029156
33028108 PDF 2020. Clarification of the Role of miR-9 in the Angiogenesis, Migration, and Autophagy of Endothelial Progenitor Cells Through RNA Sequence Analysis.Template:33028108
16399784 PDF 2006. Functional expression of transient receptor potential melastatin- and vanilloid-related channels in pulmonary arterial and aortic smooth muscle.Template:16399784
16120184 PDF 2005. Emerging functions of 10 types of TRP cationic channel in vascular smooth muscle.Template:16120184
35353635 PDF 2022. Role of mechanosensitive channels/receptors in atherosclerosis.Template:35353635
27123953 PDF 2016. The relationship between elevated magnesium levels and coronary artery ectasia.Template:27123953
27419135 PDF 2016. Magnesium Attenuates Phosphate-Induced Deregulation of a MicroRNA Signature and Prevents Modulation of Smad1 and Osterix during the Course of Vascular Calcification.Template:27419135
25416190 PDF 2015. Role of TRP channels in the cardiovascular system.Template:25416190
24025865 PDF 2013. TRP channel Ca(2+) sparklets: fundamental signals underlying endothelium-dependent hyperpolarization.Template:24025865
33969008 PDF 2021. The Cell Origin and Role of Osteoclastogenesis and Osteoblastogenesis in Vascular Calcification.Template:33969008
31187891 PDF 2019. Transient Receptor Potential Channels and Endothelial Cell Calcium Signaling.Template:31187891
29780355 PDF 2018. Therapeutic Interference With Vascular Calcification-Lessons From Klotho-Hypomorphic Mice and Beyond.Template:29780355

25667672 PDF 2015. Magnesium modulates the expression levels of calcification-associated factors to inhibit calcification in a time-dependent manner.'

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37176057 PDF 2023. The Role of Txnip in Mediating Low-Magnesium-Driven Endothelial Dysfunction.Template:37176057
33494333 PDF 2021. Magnesium Deficiency Induces Lipid Accumulation in Vascular Endothelial Cells via Oxidative Stress-The Potential Contribution of EDF-1 and PPARgamma.Template:33494333
32821726 PDF 2020. Canonical Transient Receptor Potential Channels and Vascular Smooth Muscle Cell Plasticity.Template:32821726
30662354 PDF 2019. Fibroblast Growth Factor 21 Attenuates Vascular Calcification by Alleviating Endoplasmic Reticulum Stress Mediated Apoptosis in Rats.Template:30662354
29892998 PDF 2018. Exosomes, the message transporters in vascular calcification.Template:29892998
29891771 PDF 2018. Role of Magnesium Deficiency in Promoting Atherosclerosis, Endothelial Dysfunction, and Arterial Stiffening as Risk Factors for Hypertension.Template:29891771
36984673 PDF 2023. The Interplay between TRPM7 and MagT1 in Maintaining Endothelial Magnesium Homeostasis.
36620697 PDF 2023. Vascular calcification: Molecular mechanisms and therapeutic interventions.Template:36620697
36079843 PDF 2022. The Response of the Human Umbilical Vein Endothelial Cell Transcriptome to Variation in Magnesium Concentration.Template:36079843
34444763 PDF 2021. The Emerging Role of Nutraceuticals in Cardiovascular Calcification: Evidence from Preclinical and Clinical Studies.Template:34444763
33919969 PDF 2021. High Magnesium and Sirolimus on Rabbit Vascular Cells-An In Vitro Proof of Concept.Template:33919969

31605492 PDF 2020. Calciprotein particle inhibition explains magnesium-mediated protection against vascular calcification.'

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24290571 PDF 2014. Magnesium intake is inversely associated with coronary artery calcification: the Framingham Heart Study.Template:24290571
21750166 PDF 2012. Magnesium reduces calcification in bovine vascular smooth muscle cells in a dose-dependent manner.Template:21750166
35831341 PDF 2022. Vascular calcification in different arterial beds in ex vivo ring culture and in vivo rat model.Template:35831341
32706793 PDF 2020. Elevated serum magnesium lowers calcification propensity in Memo1-deficient mice.Template:32706793
32074140 PDF 2020. Microvasculopathy and soft tissue calcification in mice are governed by fetuin-A, magnesium and pyrophosphate.Template:32074140
31142774 PDF 2019. Serum Magnesium is associated with Carotid Atherosclerosis in patients with high cardiovascular risk (CORDIOPREV Study).Template:31142774
30706178 PDF 2019. SGK1-dependent stimulation of vascular smooth muscle cell osteo-/chondrogenic transdifferentiation by interleukin-18.Template:30706178
29786640 PDF 2018. Vitamin D in Vascular Calcification: A Double-Edged Sword?Template:29786640
29389872 PDF 2018. Dietary Magnesium and Cardiovascular Disease: A Review with Emphasis in Epidemiological Studies.Template:29389872

29225900 PDF 2017. Decreased magnesium status may mediate the increased cardiovascular risk associated with calcium supplementation.'

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28581893 PDF 2017. Roles of transient receptor potential channels in regulation of vascular and epithelial barriers.Template:28581893
25834234 PDF 2015. Transient receptor potential channels in the vasculature.Template:25834234

25607936 PDF 2015. Characterisation of calcium phosphate crystals on calcified human aortic vascular smooth muscle cells and potential role of magnesium.'

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33445441 PDF 2021. Apoptosis in the Extraosseous Calcification Process.'

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27809396 PDF 2017. Redox regulation of transient receptor potential channels in the endothelium.Template:27809396
22909953 PDF 2012. Macrophage function in atherosclerosis: potential roles of TRP channels.Template:22909953
35353635 PDF 2022. Role of mechanosensitive channels/receptors in atherosclerosis.Template:35353635
27419135 PDF 2016. Magnesium Attenuates Phosphate-Induced Deregulation of a MicroRNA Signature and Prevents Modulation of Smad1 and Osterix during the Course of Vascular Calcification.Template:27419135
24025865 PDF 2013. TRP channel Ca(2+) sparklets: fundamental signals underlying endothelium-dependent hyperpolarization.Template:24025865
34504876 PDF 2021. beta-Hydroxybutyric Inhibits Vascular Calcification via Autophagy Enhancement in Models Induced by High Phosphate.Template:34504876
33969008 PDF 2021. The Cell Origin and Role of Osteoclastogenesis and Osteoblastogenesis in Vascular Calcification.Template:33969008
34003800 PDF 2021. ALKBH1-demethylated DNA N6-methyladenine modification triggers vascular calcification via osteogenic reprogramming in chronic kidney disease.Template:34003800
33716794 PDF 2021. Vascular Dysfunction in Diabetes and Obesity: Focus on TRP Channels.Template:33716794
33494333 PDF 2021. Magnesium Deficiency Induces Lipid Accumulation in Vascular Endothelial Cells via Oxidative Stress-The Potential Contribution of EDF-1 and PPARgamma.Template:33494333
33369187 PDF 2021. Role of gut microbiota-derived metabolites on vascular calcification in CKD.Template:33369187
32821726 PDF 2020. Canonical Transient Receptor Potential Channels and Vascular Smooth Muscle Cell Plasticity.Template:32821726
37441489 PDF 2023. Reduced Levels of the Antiaging Hormone Klotho are Associated With Increased Aortic Stiffness in Diabetic Kidney Disease.Template:37441489
36984673 PDF 2023. The Interplay between TRPM7 and MagT1 in Maintaining Endothelial Magnesium Homeostasis.Template:36984673
36620697 PDF 2023. Vascular calcification: Molecular mechanisms and therapeutic interventions.Template:36620697
34444763 PDF 2021. The Emerging Role of Nutraceuticals in Cardiovascular Calcification: Evidence from Preclinical and Clinical Studies.Template:34444763
32706793 PDF 2020. Elevated serum magnesium lowers calcification propensity in Memo1-deficient mice.Template:32706793
32074140 PDF 2020. Microvasculopathy and soft tissue calcification in mice are governed by fetuin-A, magnesium and pyrophosphate.Template:32074140
30706178 PDF 2019. SGK1-dependent stimulation of vascular smooth muscle cell osteo-/chondrogenic transdifferentiation by interleukin-18.Template:30706178
34938784 PDF 2021. Inflammatory Cells Accelerated Carotid Artery Calcification via MMP9: Evidences From Single-Cell Analysis.Template:34938784
34650631 PDF 2021. miR-124 promotes apoptosis and inhibits the proliferation of vessel endothelial cells through P38/MAPK and PI3K/AKT pathways, making it a potential mechanism of vessel endothelial injury in acute myocardial infarction.Template:34650631
33937254 PDF 2021. ORAI1 Ca(2+) Channel as a Therapeutic Target in Pathological Vascular Remodelling.Template:33937254
33390906 PDF 2020. The Ion Channel and GPCR Toolkit of Brain Capillary Pericytes.Template:33390906
32757967 PDF 2020. Inflammasomes: a preclinical assessment of targeting in atherosclerosis.
32161445 PDF 2020. Inhibitory Effect of Curcumin on Artery Restenosis Following Carotid Endarterectomy and Its Associated Mechanism in vitro and in vivo.Template:32161445
35002759 PDF 2021. Mechanobiology of Microvascular Function and Structure in Health and Disease: Focus on the Coronary Circulation.Template:35002759
34366887 PDF 2021. Editorial: Advances and Current Challenges in Calcium Signaling Within the Cardiovascular System.Template:34366887
30559679 PDF 2018. TRP Channels in Angiogenesis and Other Endothelial Functions.Template:30559679
35638551 PDF 2023. APOLD1 loss causes endothelial dysfunction involving cell junctions, cytoskeletal architecture, and Weibel-Palade bodies, while disrupting hemostasis.Template:35638551
35328769 PDF 2022. Pathophysiology of Atherosclerosis.Template:35328769
34299254 PDF 2021. The Role of TRPM2 in Endothelial Function and Dysfunction.Template:34299254
33233811 PDF 2020. Calciprotein Particles Cause Endothelial Dysfunction under Flow.Template:33233811
31416282 PDF 2019. Endothelial Ca(2+) Signaling, Angiogenesis and Vasculogenesis: just What It Takes to Make a Blood Vessel.Template:31416282
24204345 PDF 2013. Emerging role of TRP channels in cell migration: from tumor vascularization to metastasis.Template:24204345
18494937 PDF 2008. Na(+)-independent Mg(2+) transport sensitive to 2-aminoethoxydiphenyl borate (2-APB) in vascular smooth muscle cells: involvement of TRPM-like channels.Template:18494937
33240650 PDF 2020. Analysis of genes and underlying mechanisms involved in foam cells formation and atherosclerosis development.Template:33240650
34667238 PDF 2021. A neutralizing IL-11 antibody reduces vessel hyperplasia in a mouse carotid artery wire injury model.Template:34667238
27093159 PDF 2016. Sustained Improvement of Arterial Stiffness and Blood Pressure after Long-Term Rosuvastatin Treatment in Patients with Inflammatory Joint Diseases: Results from the RORA-AS Study.Template:27093159
22905291 PDF 2012. Update on vascular endothelial Ca(2+) signalling: A tale of ion channels, pumps and transporters.Template:22905291
37815888 PDF 2023. Sonic hedgehog signaling promotes angiogenesis of endothelial progenitor cells to improve pressure ulcers healing by PI3K/AKT/eNOS signaling.Template:37815888
36552677 PDF 2022. Oxidized High-Density Lipoprotein Induces Endothelial Fibrosis Promoting Hyperpermeability, Hypotension, and Increased Mortality.Template:36552677
35861069 PDF 2022. PLCbeta2 Promotes VEGF-Induced Vascular Permeability.Template:35861069
34422982 PDF 2021. Local FK506 implants in non-human primates to prevent early acute rejection in vascularized composite allografts.Template:34422982
33987277 PDF 2021. A narrative review of exosomes in vascular calcification.Template:33987277
32781528 PDF 2020. Mechanisms of the Osteogenic Switch of Smooth Muscle Cells in Vascular Calcification: WNT Signaling, BMPs, Mechanotransduction, and EndMT.Template:32781528
32010490 PDF 2020. Roles and Functions of Exosomal Non-coding RNAs in Vascular Aging.Template:32010490
29351417 PDF 2018. Zinc regulates vascular endothelial cell activity through zinc-sensing receptor ZnR/GPR39.Template:29351417
28412716 PDF 2017. Tanshinone IIA suppresses the progression of atherosclerosis by inhibiting the apoptosis of vascular smooth muscle cells and the proliferation and migration of macrophages induced by ox-LDL.Template:28412716
28212803 PDF 2017. Calcium Channels in Vascular Smooth Muscle.Template:28212803
25360054 PDF 2014. Fluid Mechanics, Arterial Disease, and Gene Expression.Template:25360054
21479754 PDF 2011. Fluid flow mechanotransduction in vascular smooth muscle cells and fibroblasts.Template:21479754
38132141 PDF 2023. Beyond the Basics: Unraveling the Complexity of Coronary Artery Calcification.Template:38132141
34550346 PDF 2022. Two-faced Janus: the dual role of macrophages in atherosclerotic calcification.Template:34550346
32065054 PDF 2020. T-Cell-Derived miRNA-214 Mediates Perivascular Fibrosis in Hypertension.Template:32065054
30663158 PDF 2019. Exosomes from human umbilical cord mesenchymal stem cells enhance fracture healing through HIF-1alpha-mediated promotion of angiogenesis in a rat model of stabilized fracture.Template:30663158
29514202 PDF 2018. Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness.Template:29514202
29394331 PDF 2018. Vascular smooth muscle contraction in hypertension.Template:29394331

28333380 PDF 2017. Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles.'

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27118293 PDF 2016. Vascular Fibrosis in Aging and Hypertension: Molecular Mechanisms and Clinical Implications.Template:27118293
29705934 PDF 2018. Exosomes Secreted by Adipose-Derived Stem Cells Contribute to Angiogenesis of Brain Microvascular Endothelial Cells Following Oxygen-Glucose Deprivation In Vitro Through MicroRNA-181b/TRPM7 Axis.Template:29705934
33028108 PDF 2020. Clarification of the Role of miR-9 in the Angiogenesis, Migration, and Autophagy of Endothelial Progenitor Cells Through RNA Sequence Analysis.Template:33028108
21646743 PDF 2011. Effects of serum amyloid a and lysophosphatidylcholine on intracellular calcium concentration in human coronary artery smooth muscle cells.Template:21646743
20132412 PDF 2011. Imipramine inhibition of TRPM-like plasmalemmal Mg2+ transport in vascular smooth muscle cells.Template:20132412
37238629 PDF 2023. Bidirectional TRP/L Type Ca(2+) Channel/RyR/BK(Ca) Molecular and Functional Signaloplex in Vascular Smooth Muscles.Template:37238629
36421426 PDF 2022. Citronellal Attenuates Oxidative Stress-Induced Mitochondrial Damage through TRPM2/NHE1 Pathway and Effectively Inhibits Endothelial Dysfunction in Type 2 Diabetes Mellitus.Template:36421426
35656112 PDF 2022. DR1 Activation Inhibits the Proliferation of Vascular Smooth Muscle Cells through Increasing Endogenous H(2)S in Diabetes.Template:35656112

33072245 PDF 2020. Markers of Endothelial Cells in Normal and Pathological Conditions.'

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29452094 PDF 2018. Evolving mechanisms of vascular smooth muscle contraction highlight key targets in vascular disease.Template:29452094
29433476 PDF 2018. TRPV4 regulates migration and tube formation of human retinal capillary endothelial cells.Template:29433476
26945080 PDF 2016. Endothelial SK3 channel-associated Ca2+ microdomains modulate blood pressure.Template:26945080
37627891 PDF 2023. Mechanism Analysis of Vascular Calcification Based on Fluid Dynamics.Template:37627891
37588590 PDF 2023. The role of macrophage ion channels in the progression of atherosclerosis.Template:37588590
35147077 PDF 2022. STIM1-dependent peripheral coupling governs the contractility of vascular smooth muscle cells.Template:35147077
33792900 PDF 2021. The Calcium Signaling Mechanisms in Arterial Smooth Muscle and Endothelial Cells.Template:33792900
32431625 PDF 2020. Regulation of Vessel Permeability by TRP Channels.Template:32431625
32364494 PDF 2020. Intravascular flow stimulates PKD2 (polycystin-2) channels in endothelial cells to reduce blood pressure.Template:32364494
30511640 PDF 2018. Arterial smooth muscle cell PKD2 (TRPP1) channels regulate systemic blood pressure.Template:30511640
28057793 PDF 2017. Protein Interactions at Endothelial Junctions and Signaling Mechanisms Regulating Endothelial Permeability.Template:28057793
38069089 PDF 2023. Cracking the Endothelial Calcium (Ca(2+)) Code: A Matter of Timing and Spacing.Template:38069089
31766552 PDF 2019. Ca(2+) Flux: Searching for a Role in Efferocytosis of Apoptotic Cells in Atherosclerosis.Template:31766552

24935972 PDF 2014. Endotoxin-induced endothelial fibrosis is dependent on expression of transforming growth factors beta1 and beta2.'

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23635013 PDF 2013. Lipopolysaccharide induces a fibrotic-like phenotype in endothelial cells.'

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29333215 PDF 2017. Markers and Biomarkers of Endothelium: When Something Is Rotten in the State.'

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28475214 PDF 2017. The angiotensin II receptor type 1b is the primary sensor of intraluminal pressure in cerebral artery smooth muscle cells.Template:28475214
27531064 PDF 2016. Mechanical activation of angiotensin II type 1 receptors causes actin remodelling and myogenic responsiveness in skeletal muscle arterioles.Template:27531064
25180264 PDF 2014. Vascular TRP channels: performing under pressure and going with the flow.Template:25180264
23748495 PDF 2014. Endothelial control of vasodilation: integration of myoendothelial microdomain signalling and modulation by epoxyeicosatrienoic acids.Template:23748495
22886693 PDF 2013. Myosin light chain kinase signaling in endothelial barrier dysfunction.Template:22886693

25610592 PDF 2014. Mechanisms regulating endothelial permeability.'

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20966350 PDF 2010. Klotho is associated with VEGF receptor-2 and the transient receptor potential canonical-1 Ca2+ channel to maintain endothelial integrity.Template:20966350
35163382 PDF 2022. A Central Role for TRPM4 in Ca(2+)-Signal Amplification and Vasoconstriction.Template:35163382
28412716 PDF 2017. Tanshinone IIA suppresses the progression of atherosclerosis by inhibiting the apoptosis of vascular smooth muscle cells and the proliferation and migration of macrophages induced by ox-LDL.Template:28412716
38089479 PDF 2023. Research progress on the mechanism of angiogenesis in wound repair and regeneration.Template:38089479
36786037 PDF 2023. Exosomes for angiogenesis induction in ischemic disorders.Template:36786037
34992411 PDF 2021. Spotlight on NLRP3 Inflammasome: Role in Pathogenesis and Therapies of Atherosclerosis.Template:34992411