TRPM8
as i had the scabies i felt innerly cold as ice. not based.
18684990 PDF 2008. Cooling skin cancer: menthol inhibits melanoma growth. Focus on "TRPM8 activation suppresses cellular viability in human melanoma".Template:18684990
37857704 PDF 2023. Structure of human TRPM8 channel.Template:37857704
35662242 PDF 2022. Structures of a mammalian TRPM8 in closed state.Template:35662242
31488702 PDF 2019. Structural insights into TRPM8 inhibition and desensitization.Template:31488702
29217583 PDF 2018. Structure of the cold- and menthol-sensing ion channel TRPM8.Template:29217583
37373205 PDF 2023. Human Osteoarthritic Chondrocytes Express Nineteen Different TRP-Genes-TRPA1 and TRPM8 as Potential Drug Targets.Template:37373205
33655414 PDF 2021. Linalool inhibits the angiogenic activity of endothelial cells by downregulating intracellular ATP levels and activating TRPM8.Template:33655414
28053885 PDF 2017. Shakuyakukanzoto attenuates oxaliplatin-induced cold dysesthesia by inhibiting the expression of transient receptor potential melastatin 8 in mice.Template:28053885
27131832 PDF 2016. Topical menthol increases cutaneous blood flow.Template:27131832
23441811 PDF 2013. Cold stress induces lower urinary tract symptoms.Template:23441811
26657057 PDF 2016. Phosphoinositide interacting regulator of TRP (Pirt) enhances TRPM8 channel activity in vitro via increasing channel conductance.Template:26657057
24372189 PDF 2014. TRP channels in the skin.Template:24372189
34734022 PDF 2021. Cold-inducible RNA-binding protein migrates from the nucleus to the cytoplasm under cold stress in normal human bronchial epithelial cells via TRPM8-mediated mechanism.Template:34734022
34589786 PDF 2021. Role of TRPM8 in switching between fever and hypothermia in adult mice during endotoxin-induced inflammation.Template:34589786
32400133 PDF 2020. Activation of Transient Receptor Potential Melastatin Family Member 8 (TRPM8) Receptors Induces Proinflammatory Cytokine Expressions in Bronchial Epithelial Cells.Template:32400133
31216483 PDF 2019. Direct Galpha(q) Gating Is the Sole Mechanism for TRPM8 Inhibition Caused by Bradykinin Receptor Activation.Template:31216483
29972224 PDF 2018. Modulation of Itch by Localized Skin Warming and Cooling.Template:29972224
26536261 PDF 2015. Functional and Modeling Studies of the Transmembrane Region of the TRPM8 Channel.Template:26536261
26341484 PDF 2015. Redox and trace metal regulation of ion channels in the pain pathway.Template:26341484
25894692 PDF 2015. Molecular and cellular mechanisms that initiate pain and itch.Template:25894692
23850286 PDF 2013. Polyester modification of the mammalian TRPM8 channel protein: implications for structure and function.Template:23850286
23651844 PDF 2013. Enhanced insulin clearance in mice lacking TRPM8 channels.Template:23651844
22860192 PDF 2012. Modulation of thermoreceptor TRPM8 by cooling compounds.Template:22860192
19203589 PDF 2009. Roles of transient receptor potential channels in pain.Template:19203589
37781093 PDF 2023. Peripheral mechanisms of peripheral neuropathic pain.Template:37781093
36439160 PDF 2022. Cold stimuli, hot topic: An updated review on the biological activity of menthol in relation to inflammation.Template:36439160
35847920 PDF 2022. Comprehensive Pan-Cancer Analysis of TRPM8 in Tumor Metabolism and Immune Escape.Template:35847920
31293565 PDF 2019. Pruritus in Autoimmune and Inflammatory Dermatoses.Template:31293565
26242276 PDF 2015. Pilot study to determine whether transient receptor potential melastatin type 8 (TRPM8) antibodies are detected in scleroderma.Template:26242276
21903934 PDF 2011. Menthol attenuates respiratory irritation responses to multiple cigarette smoke irritants.Template:21903934
36675074 PDF 2023. Pathogenesis and Treatment of Pruritus Associated with Chronic Kidney Disease and Cholestasis.Template:36675074
36536695 PDF 2022. Global Trends and Hotspots of Transient Receptor Potential Melastatin 8 Research from 2002 to 2021: A Bibliometric Analysis.Template:36536695
35897101 PDF 2022. Activation of peripheral TRPM8 mitigates ischemic stroke by topically applied menthol.Template:35897101
34446569 PDF 2021. Constitutive Phosphorylation as a Key Regulator of TRPM8 Channel Function.Template:34446569
31114308 PDF 2019. Intrathecal TRPM8 blocking attenuates cold hyperalgesia via PKC and NF-kappaB signaling in the dorsal root ganglion of rats with neuropathic pain.Template:31114308
30545944 PDF 2019. The Immunosuppressant Macrolide Tacrolimus Activates Cold-Sensing TRPM8 Channels.Template:30545944
29880642 PDF 2018. Critical role of the pore domain in the cold response of TRPM8 channels identified by ortholog functional comparison.Template:29880642
29530988 PDF 2018. Deletion of the Cold Thermoreceptor TRPM8 Increases Heat Loss and Food Intake Leading to Reduced Body Temperature and Obesity in Mice.Template:29530988
27845197 PDF 2017. Sustained Morphine Administration Induces TRPM8-Dependent Cold Hyperalgesia.Template:27845197
27634619 PDF 2016. TRPM8 and Migraine.Template:27634619
25157108 PDF 2014. The region adjacent to the C-end of the inner gate in transient receptor potential melastatin 8 (TRPM8) channels plays a central role in allosteric channel activation.Template:25157108
24917670 PDF 2014. Bidirectional modulation of thermal and chemical sensitivity of TRPM8 channels by the initial region of the N-terminal domain.Template:24917670
23884957 PDF 2013. Artemin, a glial cell line-derived neurotrophic factor family member, induces TRPM8-dependent cold pain.Template:23884957
22323721 PDF 2012. Pharmacological blockade of the cold receptor TRPM8 attenuates autonomic and behavioral cold defenses and decreases deep body temperature.Template:22323721
21900509 PDF 2011. TRPM8 acute desensitization is mediated by calmodulin and requires PIP(2): distinction from tachyphylaxis.Template:21900509
21282398 PDF 2011. Voltage- and cold-dependent gating of single TRPM8 ion channels.Template:21282398
18077679 PDF 2007. TRPM8 mechanism of cold allodynia after chronic nerve injury.Template:18077679
36966947 PDF 2023. Neuronal loss of TRPM8 leads to obesity and glucose intolerance in male mice.Template:36966947
36295712 PDF 2022. Nebivolol as a Potent TRPM8 Channel Blocker: A Drug-Screening Approach through Automated Patch Clamping and Ligand-Based Virtual Screening.Template:36295712
35997391 PDF 2022. Pathophysiology of Nociception and Rare Genetic Disorders with Increased Pain Threshold or Pain Insensitivity.Template:35997391
34834317 PDF 2021. The Use of Menthol in Skin Wound Healing-Anti-Inflammatory Potential, Antioxidant Defense System Stimulation and Increased Epithelialization.Template:34834317
34717968 PDF 2022. Menthol-induced activation of TRPM8 receptors increases cutaneous blood flow across the dermatome.Template:34717968
32955611 PDF 2021. TRPV4 and TRPM8 as putative targets for chronic low back pain alleviation.Template:32955611
32728032 PDF 2020. Molecular mechanisms underlying menthol binding and activation of TRPM8 ion channel.Template:32728032
32290846 PDF 2020. Chronic morphine regulates TRPM8 channels via MOR-PKCbeta signaling.Template:32290846
31869278 PDF 2020. Physiology and Pathophysiology of Itch.Template:31869278
29541177 PDF 2018. RNA interference-mediated depletion of TRPM8 enhances the efficacy of epirubicin chemotherapy in prostate cancer LNCaP and PC3 cells.Template:29541177
29164310 PDF 2018. Relevance of TRPA1 and TRPM8 channels as vascular sensors of cold in the cutaneous microvasculature.Template:29164310
| 29088850 PDF 2017. Dietary menthol-induced TRPM8 activation enhances WAT "browning" and ameliorates diet-induced obesity.' |
28358322 PDF 2017. Development of TRPM8 Antagonists to Treat Chronic Pain and Migraine.Template:28358322
28039451 PDF 2017. High-throughput proteome analysis reveals targeted TRPM8 degradation in prostate cancer.Template:28039451
28038937 PDF 2017. Cellular permeation of large molecules mediated by TRPM8 channels.Template:28038937
27131832 PDF 2016. Topical menthol increases cutaneous blood flow.Template:27131832
26870186 PDF 2016. Anti-tumor activity of the TRPM8 inhibitor BCTC in prostate cancer DU145 cells.Template:26870186
25433072 PDF 2015. Molecular mechanisms of temperature adaptation.Template:25433072
22571355 PDF 2012. Transient receptor potential melastatin 8 (TRPM8) channels are involved in body temperature regulation.Template:22571355
22292988 PDF 2012. L type Ca(2)+ channel blockers prevent oxaliplatin-induced cold hyperalgesia and TRPM8 overexpression in rats.Template:22292988
22061619 PDF 2012. Regulation of TRPM8 channel activity.Template:22061619
18534015 PDF 2008. TRPM8 mechanism of autonomic nerve response to cold in respiratory airway.Template:18534015
17317754 PDF 2007. Bidirectional shifts of TRPM8 channel gating by temperature and chemical agents modulate the cold sensitivity of mammalian thermoreceptors.Template:17317754
36227998 PDF 2022. Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP(2).Template:36227998
32843690 PDF 2020. Highly functionalized beta-lactams and 2-ketopiperazines as TRPM8 antagonists with antiallodynic activity.Template:32843690
32220960 PDF 2020. A paradigm of thermal adaptation in penguins and elephants by tuning cold activation in TRPM8.Template:32220960
31575973 PDF 2019. Competitive Interactions between PIRT, the Cold Sensing Ion Channel TRPM8, and PIP(2) Suggest a Mechanism for Regulation.Template:31575973
27227023 PDF 2015. Biophysical analysis of thermosensitive TRP channels with a special focus on the cold receptor TRPM8.Template:27227023
21767774 PDF 2011. Topical therapies for pruritus.Template:21767774
17183631 PDF 2006. Neural substrate of cold-seeking behavior in endotoxin shock.Template:17183631
37033630 PDF 2023. Therapeutic potential of TRPM8 channels in cancer treatment.Template:37033630
33344232 PDF 2020. Transient Receptor Potential Melastatin 8 (TRPM8) Channel Regulates Proliferation and Migration of Breast Cancer Cells by Activating the AMPK-ULK1 Pathway to Enhance Basal Autophagy.Template:33344232
37834183 PDF 2023. Pathomechanism of Pruritus in Psoriasis and Atopic Dermatitis: Novel Approaches, Similarities and Differences.Template:37834183
34445208 PDF 2021. TRPM8 Channels: Advances in Structural Studies and Pharmacological Modulation.Template:34445208
34861341 PDF 2022. Role of TRP ion channels in pruritus.Template:34861341
29282613 PDF 2018. Regulation of Pain and Itch by TRP Channels.Template:29282613
15847696 PDF 2005. How cold is it? TRPM8 and TRPA1 in the molecular logic of cold sensation.Template:15847696
30858386 PDF 2019. ADP-Ribose and oxidative stress activate TRPM8 channel in prostate cancer and kidney cells.Template:30858386
27983625 PDF 2016. TRP Channels in Skin Biology and Pathophysiology.Template:27983625